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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Comorbid situs inversus totalis and schizophrenia in a young male
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Comorbid situs inversus totalis and schizophrenia in a young male

机译:Comorbid satus virersus totalis和schizophrenia在一个年轻的男性

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摘要

Situs inversus is an autosomal recessive disorder of lateralization that is present in I in 10,000 live births (Kennedy et al., 1999). Previous case descriptions have linked psychosis or schizophrenia with a related condition, Kartagener's syndrome (prevalence approximately I in 30,000 to 60,000 live births) that additionally involves primary ciliary dyskinesia (PCD) (Quast et al., 2005). We describe here for the first time the comorbid presentation of schizophrenia and situs inversus totalis (SIT) in an intellectually normal and otherwise healthy young male without PCD and speculate on the role of abnormal lateralization in schizophrenia.An 18-year-old male with SIT was referred for psychiatric crisis assessment with a 3-month history of paranoid delusions. There was no prior psychiatric or substance use history and no family history of psychiatric illness, SIT, or Kartagener's syndrome. He was born full term with no antenatal, obstetric or post-natal complications. At age 18 months, he was diagnosed incidentally with SIT but has not experienced bronchiectasis, chronic sinusitis, or other disorders associated with PCD.
机译:SITUS virersus是一种肠道内化的常染色体隐性障碍,其在10,000个活产前存在(Kennedy等,1999)。以前的病例描述与相关病症有关的精神病或精神分裂症,Karteragener的综合征(患病率约为30,000至60,000个活产出生),另外涉及主要睫状体缺乏症(PCD)(Quast等,2005)。我们在这里描述了在这里首次描述了精神分裂症和SITUS VILESSUS(SIT)在没有PCD的智力正常和其他健康的年轻男性中,并推测了精神分裂症中异常侧向化的作用。18岁的男性与坐着被称为精神病危机评估,偏执困难的3个月历史。没有先前的精神病或物质使用历史,没有精神疾病的家族史,坐着或karteragener的综合症。他出生了全年,没有产前,产科或产后并发症。年龄在18个月,他偶然诊断出坐着,但没有经历过支气管扩张,慢性鼻窦炎或与PCD相关的其他疾病。

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