...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The British journal of psychiatry : >Association between particulate matter air pollution and risk of depression and suicide: systematic review and meta-analysis
【24h】

Association between particulate matter air pollution and risk of depression and suicide: systematic review and meta-analysis

机译：颗粒物质空气污染与抑郁症风险与抑郁和自杀的关联：系统审查和荟萃分析

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background Some recent studies examined the effect of ambient particulate matter (PM) pollution on depression and suicide. However, the results have been inconclusive. Aims To determine the overall relationship between PM exposure and depression/suicide in the general population. Method We conducted a systematic review and meta-analysis of case-crossover and cohort studies to assess the association between PM2.5 (particles with an aerodynamic diameter of 2.5 mu m or less) or PM10 (particles with an aerodynamic diameter between 2.5 and 10 mu m) exposure and depression/suicide. Results A total of 14 articles (7 for depression and 7 for suicide) with data from 684 859 participants were included in the meta-analysis. With a 10 mu g/m3 increase in PM2.5 we found a 19% (odds ratio [95% CI] 1.19 [1.07, 1.33]) increased risk of depression and a marginally increased risk of suicide (odds ratio [95% CI] 1.05 [0.99, 1.11]) in the general population. We did not observe any significant associations between increasing exposure to PM10 and depression/suicide. Sensitivity and subgroup analyses were used to determine the robustness of results. The strongest estimated effect of depression associated with PM2.5 appeared in a long-term lag pattern (odds ratio [95% CI] 1.25 [1.07, 1.45], P < 0.01) and cumulative lag pattern (odds ratio [95% CI] 1.26 [1.07, 1.48], P < 0.01). Conclusions The meta-analysis suggested that an increase in ambient PM2.5 concentration was strongly associated with increased depression risk in the general population, and the association appeared stronger at long-term lag and cumulative lag patterns, suggesting a potential cumulative exposure effect over time. Declaration of interest None.
机译：背景技术一些最近的研究检测了环境颗粒物质（PM）污染对抑郁和自杀的影响。但是，结果一直不确定。旨在确定PM PM暴露和抑郁/自杀的整体关系。方法我们进行了系统审查和荟萃分析的案例交叉和队列研究，以评估PM2.5（空气动力直径为2.5μm或更小的颗粒）或PM10（空气动力学直径为2.5和10之间的颗粒之间的关联mu m）暴露和抑郁/自杀。结果在Meta分析中，共有14篇（用于抑郁症和自杀的7种）和7种，其中7种和7种）的数据包括来自684个859名参与者的数据。 PM2.5的10μg/ m 3增加我们发现19％（差距[95％ci] 1.19 [1.07,19.33]）增加抑郁风险和略微增加的自杀风险（差异比例[95％ci [95％在一般人群中，1.05 [0.99,1.11]）。我们在增加PM10和抑郁/自杀之间的情况下没有观察到任何重要的协会。敏感性和子组分析用于确定结果的稳健性。与PM2.5相关的抑郁症的最强估计效应出现在长期滞后模式（差距[95％CI] 1.25 [1.07,1.45]，P <0.01）和累积滞后模式（差距比例[95％CI]） 1.26 [1.07,1.48]，P <0.01）。结论META分析表明，环境PM2.5浓度的增加与一般人群的抑郁症风险增加强烈有关，并且在长期滞后和累积滞后模式下，该关联似乎更强烈，这表明潜在的累积暴露效应随着时间的推移。申报感兴趣没有。

著录项

  • 来源
  • 作者

    Gu Xuelin; Liu Qisijing; Deng Furong; Wang Xueqin; Lin Hualiang; Guo Xinbiao; Wu Shaowei;

  • 作者单位

    Peking Univ Dept Occupat &

    Environm Hlth Sci Sch Publ Hlth 38 Xueyuan Rd Beijing 100191;

    Peking Univ Dept Occupat &

    Environm Hlth Sci Sch Publ Hlth 38 Xueyuan Rd Beijing 100191;

    Peking Univ Dept Occupat &

    Environm Hlth Sci Sch Publ Hlth 38 Xueyuan Rd Beijing 100191;

    Peking Univ Inst Mental Hlth Key Lab Mental Hlth Minist Hlth Hosp 6 Natl Clin Res Ctr Mental;

    Sun Yat Sen Univ Sch Publ Hlth Dept Med Stat &

    Epidemiol Guangzhou Guangdong Peoples R China;

    Peking Univ Dept Occupat &

    Environm Hlth Sci Sch Publ Hlth 38 Xueyuan Rd Beijing 100191;

    Peking Univ Dept Occupat &

    Environm Hlth Sci Sch Publ Hlth Key Lab Mol Cardiovasc Sci Minist;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 精神病学;
  • 关键词

    Particulate matter; depression; suicide; meta-analysis;

    机译：颗粒物质;抑郁症;自杀;荟萃分析;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号