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Association of cardiorespiratory fitness on interhemispheric hippocampal and parahippocampal functional connectivity

机译:互脱血球海马和总体砍地淘汰功能连通性的心肺健身协会

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摘要

Interhemispheric functional connectivity is associated with cognitive functioning. Although previous work has evaluated the association of cardiorespiratory fitness on cognitive function, there has been a limited investigation of the association of cardiorespiratory fitness on the functional connectivity of memory-related brain structures. As such, the objective of this study was to examine the association between cardiorespiratory fitness and parahippocampal and hippocampal interhemispheric functional connectivity. Data from the Nathan Kline Institute-Rockland Sample (NKI-RS) were utilized. Our analysis consisted of 284 participants (M-age = 43 years; 62% female). Cardiorespiratory fitness was objectively measured using a cycle ergometer protocol. Parahippocampal and hippocampal interhemispheric functional connectivity were assessed from fMRI. Higher cardiorespiratory fitness was associated with greater parahippocampal (beta = 0.004; CI, 0.00009 to 0.008, p = 0.04), but not hippocampal (beta = 0.001; CI, -0.002 to 0.005, p = 0.44) interhemispheric functional connectivity. In conclusion, enhanced cardiorespiratory fitness may facilitate parahippocampal interhemispheric functional connectivity.
机译:互脱型功能连接与认知功能有关。虽然以前的工作已经评估了心肺功能性对认知功能的关联,但有限调查了内透视适应对内存相关脑结构功能连通性的关联。因此,本研究的目的是检查心肺刺激性健身和总产阶级疫苗和海马互际功能连通性之间的关联。利用了Nathan Kline Institute-Rockland样本(NKI-RS)的数据。我们的分析由284名参与者(M龄= 43岁; 62%)组成。使用循环钻头协议客观地测量心肺功能性。从FMRI评估总比帕帕帕帕和海马间斜际功能连接。较高的心肺功能性与更高的PARAHIPPocampal(β= 0.004; CI,0.00009至0.008,P = 0.04)相关,但不是海马(β= 0.001; CI,-0.002至0.005,P = 0.44)互脱间球功能连通性。总之,增强的心肺健身可以促进总体疫苗的间隙功能连通性。

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