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首页> 外文期刊>The European Journal of Neuroscience >The relationship between individual differences in gray matter volume and religiosity and mystical experiences: A preregistered voxel-based morphometry study
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The relationship between individual differences in gray matter volume and religiosity and mystical experiences: A preregistered voxel-based morphometry study

机译：灰质体积与宗教信仰与神秘体验的个体差异的关系：基于葡萄素的更预期的形态学研究

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摘要

The neural substrates of religious belief and experience are an intriguing though contentious topic. Here, we had the unique opportunity to establish the relation between validated measures of religiosity and gray matter volume in a large sample of participants (N = 211). In this registered report, we conducted a confirmatory voxel-based morphometry analysis to test three central hypotheses regarding the relationship between religiosity and mystical experiences and gray matter volume. The preregisterered hypotheses, analysis plan, preprocessing and analysis code and statistical brain maps are all available from online repositories. By using a region-of-interest analysis, we found no evidence that religiosity is associated with a reduced volume of the orbito-frontal cortex and changes in the structure of the bilateral inferior parietal lobes. Neither did we find support for the notion that mystical experiences are associated with a reduced volume of the hippocampus, the right middle temporal gyrus or with the inferior parietal lobes. A whole-brain analysis furthermore indicated that no structural brain differences were found in association with religiosity and mystical experiences. We believe that the search for the neural correlates of religious beliefs and experiences should therefore shift focus from studying structural brain differences to a functional and multivariate approach.
机译：宗教信仰和经验的神经基板是一种有趣的话题虽然有趣的话题。在这里，我们拥有独特的机会，可以在大型参与者样本中建立验证措施与灰质体积之间的关系（n = 211）。在本次报告中，我们进行了基于验证的体文形态学分析，以测试有关宗教与神秘体验与灰质体积之间的关系的三个中央假设。总预期的假设，分析计划，预处理和分析代码和统计脑地图都可以从在线存储库获得。通过使用地区的兴趣区分析，我们发现没有证据表明宗教性与减少的胰腺癌体积减少相关，以及双侧下垂叶结构的变化。我们也没有找到对神秘体验与海马体积减少，右中间时颞波氏或劣质叶片相关的概念的支持。此外，全脑分析表明，没有与宗教和神秘体验结合的结构脑差异。因此，我们认为寻求宗教信仰和经验的神经关联应将重点转移到研究结构脑差异与功能和多变量的方法。

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