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首页> 外文期刊>The European Journal of Neuroscience >Bilateral lesions of the paraventricular hypothalamic nucleus disrupt nursing behavior in rabbits
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Bilateral lesions of the paraventricular hypothalamic nucleus disrupt nursing behavior in rabbits

机译：椎间盘下丘脑核的双侧病变中断兔子的护理行为

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摘要

Doe rabbits nurse the litter only once a day, for around 3min, with circa 24-h periodicity. To explore the participation of the paraventricular nucleus (PVN) in regulating this behavior, we lesioned it bilaterally with kainic acid on lactation day 7. Bilateral lesions, comprising less than 50% of the total PVN volume, abolished nursing behavior (4/8 does) or severely disrupted its normal periodicity (4/8 does). In the latter case, duration of nursing bouts was normal. Body weight, food and water intake were not significantly affected by bilateral PVN lesions. Unilateral lesions of the PVN or lesions located outside this nucleus did not significantly alter nursing periodicity or any other behavioral parameter. Results indicate an important role of the PVN for (i) maintaining maternal behavior, and (ii) the periodic display of nursing across lactation in rabbits.
机译：Doe兔子每天只护理一次垃圾，约3分钟，大约24小时周期性。 为了探讨椎间盘（PVN）的参与调节这种行为，我们用KainiC酸性致死于哺乳期第7天。双侧病变，包含总PVN体积的50％，废除护理行为（4/8 ）或严重破坏其正常周期（4/8）。 在后一种情况下，护理持续时间正常。 体重，食物和水摄入量不受双侧PVN病变的显着影响。 位于该核外的PVN或病变的单侧病变并未显着改变护理周期或任何其他行为参数。 结果表明PVN（i）维持母体行为的重要作用，（ii）兔泌乳的护理周期性显示。

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