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首页> 外文期刊>The European physical journal, E. Soft matter >Collective behavior of red blood cells in confined channels
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Collective behavior of red blood cells in confined channels

机译：密闭渠道红细胞的集体行为

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We study the flow properties of red blood cells in confined channels, when the channel width is comparable to the cell size. We focus on the case of intermediate concentrations when hydrodynamic interactions between cells play a dominant role. This regime is different to the case of low concentration in which the cells behave as hydrodynamically isolated. In this last case, the dynamic behavior is entirely controlled by the interplay between the interaction with the wall and the elastic response of the cell membrane. Our results highlight the different fluid properties when collective flow is present. The cells acquire a characteristic slipper shape, and parachute shapes are only observed at very large capillary numbers. We have characterized the spatial ordering and the layering by means of a pairwise correlation function. Focusing effects are observed at the core of the channel instead of at the lateral position typical of the single-train case. These results indicate that at these intermediate concentrations we observed at the microscale the first steps of the well-known macroscopic Fahraeus-Lindqvist effect. The rheological properties of the suspension are studied by means of the effective viscosity, with an expected shear-thinning behavior. Two main differences are obtained with respect to the single-train case. First, a large magnitude of the viscosity is obtained indicating a high resistance to flow. Secondly, the shear-thinning behavior is obtained at larger values of the capillary number respect to the single-train case. These results suggest that the phenomena of ordering in space and orientation occur at higher values of the capillary number.
机译：当沟道宽度与电池尺寸相当时，我们研究限制通道中红细胞的流动性质。当细胞之间的流体动力学相互作用发挥显着作用时，我们专注于中间浓度的情况。该制度与低浓度的情况不同，其中细胞表现为流体动力学分离。在最后一个情况下，动态行为完全由与壁的相互作用与细胞膜的弹性响应之间的相互作用控制。当存在集体流动时，我们的结果突出了不同的流体性质。细胞获取特征拖鞋形状，并且仅在非常大的毛细管数中观察到降落伞形状。我们通过成对相关函数表征了空间排序和分层。在通道的核心中观察到聚焦效果，而不是在单列列车壳的典型横向位置处。这些结果表明，在这些中间浓度下，我们在微尺寸观察到众所周知的宏观Fahraeus-lindqvist效应的第一步。通过有效粘度研究悬浮液的流变性质，具有预期的剪切稀释行为。关于单列车案件获得了两个主要差异。首先，获得粘度的较大幅度，表示具有高耐流量的耐受性。其次，在毛细管数量的较大值方面获得剪切变薄行为，对单列车壳。这些结果表明，空间和取向的排序现象发生在毛细数量的较高值下。

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