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首页> 外文期刊>The British Journal of Nutrition >Does maternal smoking in pregnancy explain the differences in the body composition trajectory between breastfed and formula-fed infants?
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Does maternal smoking in pregnancy explain the differences in the body composition trajectory between breastfed and formula-fed infants?

机译：孕妇在妊娠中是否解释了母乳喂养和配方喂养婴儿之间的身体成分轨迹的差异？

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Growth patterns are known to differ between breastfed and formula-fed infants, but little is known about the relative impact of maternal smoking in pregnancy v. feeding mode on growth trajectory in infancy. We conducted a secondary analysis of a trial, the Tolerance of Infant Goat Milk Formula and Growth Assessment trial involving 290 healthy infants, to examine whether smoking in pregnancy modified the association between feeding mode and body composition of infants. Fat mass (FM) and fat-free mass (FFM) were estimated at 1, 2, 3, 4, 6 and 12 months of age using bioimpedance spectroscopy. Formula-fed infants (n 190) had a higher mean FFM at 4 months (mean difference (MD) 160 g, 95 % CI 50·4, 269·5 g, P < 0·05)) and 6 months (MD 179 g, 95 % CI 41·5, 316·9 g, P < 0·05) compared with the breastfed infants (n 100). Sub-group analysis of breastfed v. formula-fed infants by maternal smoking status in pregnancy showed that there were no differences in the FM and FFM between the breastfed and formula-fed infants whose mothers did not smoke in pregnancy. Formula-fed infants whose mothers smoked in pregnancy were smaller at birth and had a lower FM% and higher FFM% at 1 month compared with infants of non-smoking mothers regardless of feeding mode, but the differences were not significant at other time points. Adequately powered prospective studies with an appropriate design are warranted to better understand the relative impact of maternal smoking, feeding practice and the growth trajectory of infants.
机译：已知生长模式在母乳喂养和配方婴儿之间有所不同，但是关于孕妇吸烟的相对影响毫无疑问v。婴儿期生长轨迹的饲养模式。我们对试验进行了次要分析，婴儿山羊牛奶配方和增长评估试验涉及290名健康婴儿的耐受性，以检查是否在妊娠中吸烟改性喂食模式和身体组成之间的关联。使用生物阻抗光谱估计脂肪质量（FM）和无脂肪质量（FFM）在1,2,3,4,6和12个月内估计。配方喂养婴儿（N 190）在4个月（平均差（MD）160g，95％CI 50·4,269·5g，P <0·05）））和6个月（MD 179与母乳喂养婴儿（N 100）相比，G，95％CI 41·5,316·9g，p <0·05）。母乳喂养的亚组分析。孕产妇吸烟状况的公式喂养婴儿表明，母乳喂养和配方婴儿之间的FM和FFM没有差异，其母亲在怀孕中没有吸烟。配方喂养婴儿在怀孕中熏制的母亲在出生时较小，与无烟母亲的婴儿在1个月内较低的FM％和更高的FFM％，而不管喂食模式，差异在其他时间点并不重要。有充分的供电，具有适当设计的预期研究是有必要更好地理解母亲吸烟，喂养实践和婴儿生长轨迹的相对影响。

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