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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >The International Incidence of Traumatic Brain Injury: A Systematic Review and Meta-Analysis
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The International Incidence of Traumatic Brain Injury: A Systematic Review and Meta-Analysis

机译：创伤性脑损伤的国际发病率：系统审查和荟萃分析

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Background: Understanding the epidemiology of traumatic brain injury (TBI) is essential to shape public health policy, implement prevention strategies, and justify allocation of resources toward research, education, and rehabilitation in TBI. There is not, to our knowledge, a systematic review of population-based studies addressing the epidemiology of TBI that includes all subtypes. We performed a comprehensive systematic review and meta-analysis of the worldwide incidence of TBI. Methods: A search was conducted on May 23, 2014, in Medline and EMBASE according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Abstracts were screened independently and in duplicate to identify original research. Study quality and ascertainment bias were assessed in duplicate using a previously published tool. Demographic data and incidence estimates from each study were recorded, along with stratification by age, gender, year of data collection, and severity. Results: The search strategy yielded 4944 citations. Two hundred and sixteen articles met criteria for full-text review; 144 were excluded. Hand searching resulted in ten additional articles. Eighty-two studies met all eligibility criteria. The pooled annual incidence proportion for all ages was 295 per 100,000 (95% confidence interval: 274-317). The pooled incidence rate for all ages was 349 (95% confidence interval: 96.2-1266) per 100,000 person-years. Incidence proportion and incidence rate were examined to see if associated with age, sex, country, or severity. Conclusions: We conclude that most TBIs are mild and most TBIs occur in males among the adult population. The incidence of TBI varies widely by ages and between countries. Despite being an important medical, economic, and social problem, the global epidemiology of TBI is still not well-characterized in the current literature. Understanding the incidence of TBI, particularly mild TBI, remains challenging because of nonstandardized reporting among neuroepidemiological studies.
机译：背景：了解创伤性脑损伤的流行病学（TBI）对于塑造公共卫生政策，实施预防策略，以及对TBI中的研究，教育和康复的资源分配是必不可少的。据我们所知，没有对涉及所有亚型的TBI流行病学的基于人口的研究进行了系统审查。我们对TBI的全球发病率进行了全面的系统审查和荟萃分析。方法：根据系统评价和Meta分析指南的首选报告项目，在Medline和Embase进行了搜索。摘要独立筛选，并重复识别原始研究。使用先前发布的工具重复评估研究质量和确定偏差。记录了每个研究的人口统计数据和发病率，以及按年龄，性别，数据收集年度和严重程度的分层。结果：搜索策略产生了4944个引文。两百十六篇符合全文审查的标准; 144被排除在外。手搜索导致了十种附加文章。八十二项研究达到了所有资格标准。所有年龄段的汇总年发病率比例为每10万人295（95％置信区间：274-317）。所有年龄段的汇总发病率为每10万人为349（95％置信区间：96.2-1266）。检查发病率和发病率是否与年龄，性别，国家或严重程度有关。结论：我们得出结论，大多数TBIS都是轻度，大多数TBIS发生在成年人口中的男性中。 TBI的发病率因年龄段和国家之间而异。尽管是一个重要的医学，经济和社会问题，但TBI的全球流行病学仍然没有很好地表征目前的文献。了解TBI，特别是轻度TBI的发病率仍然挑战，因为神经能源学研究的非标准报告。

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