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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >P.021 Esophageal cooling for hypoxic ischemic encephalopathy: a feasibility study
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P.021 Esophageal cooling for hypoxic ischemic encephalopathy: a feasibility study

机译：P.021缺氧缺血性脑病的食管冷却：可行性研究

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摘要

Background: Targeted temperature management (TTM) is a recognized treatment to decrease mortality and improve neurological functionin hypoxic ischemic encephalopathy (HIE). An esophageal cooling device (ECD) has been studied in animal models but human data is limited. ECD appear to offer similar benefits to intravascular cooling catheters with potentially less risk to the patient. We studied whether the ECD could act as a substitute for intravascular cooling catheters. Methods: Eight ICU patients admitted following cardiac arrest who required TTM were enrolled prospectively. The primary outcome measures were timeliness of insertion, ease of insertion, user Likert ratings, time to achieve a target temperature of 36?C and time target temperature was maintained within 0.5?C of the 36?C goal for 24 hours using an ECD. Results: Time to reach target temperature 0 min to 540 min. ECD appeared to be effective at maintaining a target temperature of 36?C for most patients. In general, the catheter was easy to insert and use. Conclusions: For patients requiring TTM, use of an ECDadequately allowed for TTM goalsto be achieved and maintained. Overall user evaluationwas positive.
机译：背景：靶向温度管理（TTM）是一种公认​​的治疗，以降低死亡率，改善神经功能素低氧缺血性脑病（HIE）。在动物模型中研究了食管冷却装置（ECD），但人类数据有限。 ECD似乎为血管内冷却导管提供了类似的益处，其风险较低的患者。我们研究了ECD是否可以作为血管内冷却导管的替代品。方法：八名ICU患者患有以下需要TTM的心脏骤停均已升级。主要结果措施是插入，易于插入，用户李克特评级的及时性，实现目标温度36°C的时间，并且时间目标温度在36℃的36℃的0.5？C的目标中保持24小时，使用ECD保持24小时。结果：达到目标温度0分钟至540分钟的时间。 ECD对于大多数患者保持36℃的目标温度似乎有效。通常，导管易于插入和使用。结论：对于需要TTM的患者，使用ECDAdeQuatch允许的TTM Goalsto和维护。整体用户评估阳性。

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