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首页> 外文期刊>The Canadian journal of nursing research >Sweet Solutions for Analgesia in Neonates in China: A Systematic Review and Meta-Analysis
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Sweet Solutions for Analgesia in Neonates in China: A Systematic Review and Meta-Analysis

机译：中国新生儿镇痛的甜味溶液：系统审查和荟萃分析

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Introduction: High-quality synthesized evidence of sweet taste analgesia in neonates exists. However, Chinese databases have never been included in previous systematic reviews of sweet solutions for procedural pain. Objective: To conduct a systematic review of Chinese literature evaluating analgesic effects of sweet solutions for neonates. Data sources: Wang Fang, China National Knowledge Infrastructure and Chinese Biomedical Literature Database. Data extraction and analysis: Two authors screened studies for inclusion and conducted risk of bias ratings and data extraction. A third author resolved any conflicts. Meta-analyses were performed using RevMan 5.2 software, on mean differences in pain outcomes using random effects models. Results: Thirty-one trials (4999 neonates) were included; 26 trials used glucose, 4 used sucrose, and 1 trial evaluated both solutions. Sweet solutions reduced standardized mean pain scores (n = 21 studies; —1.68, 95% confidence interval —2.08, — 1.27) and cry duration (n = 6 studies; —25.60, 95% confidence interval —36.47, —14.72 s) but not heart rate change (n = 7 studies; —17.64, 95% confidence interval —52.71, 17.43). No included studies cited the previously published systematic reviews of sweet solutions. Conclusions: This systematic review of Chinese databases showed the same results as previously published systematic reviews. No trials included in this review cited the English systematic reviews, highlighting a parallel research agenda.
机译：介绍：在新生儿中的甜味镇痛的高质量综合证据存在。但是，中国数据库从未包含过以前的系统痛苦解决方案的系统评价。目的：对新生儿甜溶液的镇痛作用进行制系方式。数据来源：王芳，中国国家知识基础设施与中国生物医学文献数据库。数据提取和分析：两位作者筛选的纳入和进行偏置评级的风险和数据提取。第三作者解决了任何冲突。使用Revman 5.2软件进行Meta分析，在使用随机效果模型的疼痛结果的平均差异。结果：包括三十一项试验（4999个新生儿）; 26试验使用葡萄糖，4次使用的蔗糖，1试验评估了两种解决方案。甜溶液降低标准化平均疼痛评分（n = 21项研究; -1.68,95％置信区间-2.08， - 1.27）和呼啸持续时间（n = 6研究; -25.60,95％置信区间-36.47，-14.72 s）但是不是心率变化（n = 7研究; -17.64,95％置信区间-52.71,17.43）。没有包括的研究引用了以前发表的甜溶液的系统评价。结论：这种对中国数据库的系统审查显示了与以前发布的系统评论相同的结果。本评论中没有包含试验，引用了英文系统评论，突出了一个平行的研究议程。

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