Understanding real-world adherence in the directly acting antiviral era: A prospective evaluation of adherence among people with a history of drug use at a community-based program in Toronto, Canada

Mason Kate; Dodd Zoe; Guyton Mary; Tookey Paula; Lettner Bernadette; Matelski John; Sockalingam Sanjeev; Altenberg Jason; Powis Jeff

首页> 外文期刊>The International journal of drug policy >Understanding real-world adherence in the directly acting antiviral era: A prospective evaluation of adherence among people with a history of drug use at a community-based program in Toronto, Canada

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Understanding real-world adherence in the directly acting antiviral era: A prospective evaluation of adherence among people with a history of drug use at a community-based program in Toronto, Canada

机译：了解直接代理抗病毒时代的真实依从性：在加拿大多伦多的社区课程中有吸毒者历史上申诉的前瞻性评价

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Background: Direct acting antiviral (DAA) treatments for Hepatitis C (HCV) are now widely available with sustained virologic response (SVR) rates of >90%. A major predictor of response to DAAs is adherence, yet few real-world studies evaluating adherence among marginalized people who use drugs and/or alcohol exist. This study evaluates patterns and factors associated with non-adherence among marginalized people with a history of drug use who were receiving care through a primary care, community-based HCV treatment program where opiate substitution is not offered on-site.

机译：背景：目前用于丙型肝炎（HCV）的直接作用抗病毒（DAA）治疗现在广泛地提供持续的病毒学反应（SVR）率> 90％。对DAAS的反应的主要预测因子是遵守，但很少有几次实际研究评估使用药物和/或酒精的边缘化人群中的依从性。本研究评估了与初级护理历史的边缘化人群，通过初级保健，基于社区的HCV治疗方案，不提供鸦片替代的初始护理，从初始保健历史上进行边缘化的人。

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来源
《The International journal of drug policy》 |2017年第2017期|共7页
作者
Mason Kate; Dodd Zoe; Guyton Mary; Tookey Paula; Lettner Bernadette; Matelski John; Sockalingam Sanjeev; Altenberg Jason; Powis Jeff;
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作者单位

South Riverdale Community Hlth Ctr Toronto ON Canada;

South Riverdale Community Hlth Ctr Toronto ON Canada;

Sherbourne Hlth Ctr Toronto ON Canada;

South Riverdale Community Hlth Ctr Toronto ON Canada;

South Riverdale Community Hlth Ctr Toronto ON Canada;

Univ Hlth Network Biostat Res Unit Toronto ON Canada;

Univ Toronto Univ Hlth Network Ctr Mental Hlth Dept Psychiat Toronto ON Canada;

South Riverdale Community Hlth Ctr Toronto ON Canada;

Michael Garron Hosp 825 Coxwell Ave D306 Toronto ON M4C 3E7 Canada;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Hepatitis C; Direct acting antivirals; Community-based treatment models; Injection drug use; Adherence;

机译：丙型肝炎;直接代理抗病毒药人;基于社区的治疗模型;注射药物使用;坚持;

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1. Understanding real-world adherence in the directly acting antiviral era: A prospective evaluation of adherence among people with a history of drug use at a community-based program in Toronto, Canada [J] . Mason Kate, Dodd Zoe, Guyton Mary, The International journal of drug policy . 2017,第期

机译：了解直接代理抗病毒时代的真实依从性：在加拿大多伦多的社区课程中有吸毒者历史上申诉的前瞻性评价
2. Facilitators of HCV treatment adherence among people who inject drugs: a systematic qualitative review and implications for scale up of direct acting antivirals [J] . Zachary C. Rich, Carissa Chu, Jessica Mao, BMC Public Health . 2016,第1期

机译：注射药物人群中HCV治疗依从性的促进者：系统的定性评估及其对直接作用抗病毒药物大规模推广的意义
3. High adherence to all-oral directly acting antiviral HCV therapy among an inner-city patient population in a phase 2a study [J] . Petersen Tess, Townsend Kerry, Gordon Lori A., Hepatology international . 2016,第2期

机译：在2a期研究中，在内城区患者中高度坚持全口服直接作用抗病毒HCV治疗
4. Treatment Adherence and Longitudinal Clinical Outcomes in an Effectiveness Evaluation of Community-Based Multi-Family Psychoeducational Psychotherapy for Childhood Mood Disorders [D] . MacPherson, Heather Ann 2015

机译：基于社区的多家庭心理教育心理治疗对儿童情绪障碍的疗效评估中的治疗依从性和纵向临床结果
5. Adherence to Direct-Acting Antiviral Therapy in People Actively Using Drugs and Alcohol: The INCLUD Study [O] . Kristina M Brooks, Jose R Castillo-Mancilla, Mary Morrow, 2021

机译：坚持使用毒品和酗酒的人们直接抗病毒治疗：包括研究
6. Adherence to Direct-Acting Antiviral Therapy in People Actively Using Drugs and Alcohol: The INCLUD Study [O] . Kristina M Brooks, Jose R Castillo-Mancilla, Mary Morrow, 2020

机译：坚持使用毒品和酗酒的人们直接抗病毒治疗：包括研究

Understanding real-world adherence in the directly acting antiviral era: A prospective evaluation of adherence among people with a history of drug use at a community-based program in Toronto, Canada

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