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首页> 外文期刊>Protoplasma: An International Journal of Cell Biology >Mitochondrial numbers increase during glucose deprivation in the slime mold Physarum polycephalum
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Mitochondrial numbers increase during glucose deprivation in the slime mold Physarum polycephalum

机译:在粘液剥夺粘液剥落过程中的线粒体数增加了粘液模子霉菌

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摘要

Glucose deprivation in the slime mold Physarum polycephalum leads to a specific morphotype, a highly motile mesoplasmodium. We investigated the ultrastructure of both mesoplasmodia and non-starved plasmodia and found significantly increased numbers of mitochondria in glucose-deprived mesoplasmodia. The volume of individual mitochondria was the same in both growth forms. We conjecture that the number of mitochondria correlates with the metabolic state of the cell: When glucose is absent, the slime mold is forced to switch to different metabolic pathways, which occur inside mitochondria. Furthermore, a catabolic cue (such as AMP-activated protein kinase (AMPK)) could stimulate mitochondrial biogenesis.
机译:粘液剥夺粘液剥夺的粘液剥夺粘液剥夺,Polycephalum导致特定的Mor晶型,是一种高硅胺型。 我们调查了戊烯族和非饥饿疟原虫的超微结构,并发现葡萄糖剥夺的脱蛋白的线粒体数量显着增加。 两种生长形式的单个线粒体的体积相同。 据我们猜测线粒体的数量与细胞的代谢状态相关:当不存在葡萄糖时,粘液模具被迫切换到不同的代谢途径,在线粒体内发生。 此外,分解代谢提示(例如AMP活化蛋白激酶(AMPK))可以刺激线粒体生物发生。

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