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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Induced terreins production from marine red algal-derived endophytic fungus Aspergillus terreus EN-539 co-cultured with symbiotic fungus Paecilomyces lilacinus EN-531
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Induced terreins production from marine red algal-derived endophytic fungus Aspergillus terreus EN-539 co-cultured with symbiotic fungus Paecilomyces lilacinus EN-531

机译：从海洋红藻类衍生的内生真菌的生成诱导的Terreus生产与共生真菌的共生真菌患者植物霉素植物甾

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摘要

The coculture of marine red algal-derived endophytic fungi Aspergillus terreus EN-539 and Paecilomyces lilacinus EN-531 induced the production of a new terrein derivative, namely asperterrein (1) and a known dihydroterrein (2), which were not detected in the axenic cultures of both strains. The production of the known secondary metabolites terrein (3), butyrolactone I (4), and dankasterone (6), derived from A. terreus EN-539, were depressed significantly in the coculture. Compounds 1-3 exhibited inhibitory activity against Alternaria brassicae, Escherichia coli, Physalospora piricola, and Staphylococcus aureus with MIC values ranging from 4 to 64 mu g ml(-1).
机译：海洋红藻衍生的内生真菌真菌曲霉和甲状腺素烯胺，甲状腺素素烯胺酸毒素诱导诱导新的Terrein衍生物，即Asperterrein（1）和已知的Dihydroterrein（2），其在轴静脉中未检测到 两种菌株的培养。 衍生自A.Terreus EN-539的已知次级代谢物Terrein（3），丁内酯I（4）和疏松骨内酯（6）的产生在共培养中显着抑制。 化合物1-3表现出对Arrertaria Brassicae，大肠杆菌，真菌孢子孢子和金黄色葡萄球菌的抑制活性，MIC值范围为4-64μgmm（-1）。

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  • 作者

    Li Hong-Lei; Li Xiao-Ming; Yang Sui-Qun; Cao Jin; Li Yan-He; Wang Bin-Gui;

  • 作者单位

    Chinese Acad Sci Inst Oceanol Key Lab Expt Marine Biol Lab Marine Biol &

    Biotechnol Qingdao Natl;

    Chinese Acad Sci Inst Oceanol Key Lab Expt Marine Biol Lab Marine Biol &

    Biotechnol Qingdao Natl;

    Chinese Acad Sci Inst Oceanol Key Lab Expt Marine Biol Lab Marine Biol &

    Biotechnol Qingdao Natl;

    Chinese Acad Sci Inst Oceanol Key Lab Expt Marine Biol Lab Marine Biol &

    Biotechnol Qingdao Natl;

    Chinese Acad Sci Inst Oceanol Key Lab Expt Marine Biol Lab Marine Biol &

    Biotechnol Qingdao Natl;

    Chinese Acad Sci Inst Oceanol Key Lab Expt Marine Biol Lab Marine Biol &

    Biotechnol Qingdao Natl;

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  • 正文语种 eng
  • 中图分类 药学;
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