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Recent advances in the biosynthesis of nucleoside antibiotics

机译:核苷抗生素生物合成的最新进展

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摘要

Nucleoside antibiotics are a diverse class of natural products with promising biomedical activities. These compounds contain a saccharide core and a nucleobase. Despite the large number of nucleoside antibiotics that have been reported, biosynthetic studies on these compounds have been limited compared with those on other types of natural products such as polyketides, peptides, and terpenoids. Due to recent advances in genome sequencing technology, the biosynthesis of nucleoside antibiotics has rapidly been clarified. This review covering 2009-2019 focuses on recent advances in the biosynthesis of nucleoside antibiotics.
机译:核苷抗生素是一类多种自然产品,具有有前途的生物医学活动。 这些化合物含有糖核和核碱基。 尽管已经报道了大量核苷抗生素,但与其他类型的天然产物如聚酮化合物,肽和三萜类化合物相比,这些化合物的生物合成研究受到限制。 由于近期基因组测序技术的进展,核苷抗生素的生物合成迅速澄清。 该审查涵盖2009-2019侧重于核苷抗生素生物合成的最新进展。

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