首页> 外文期刊>The Journal of Antibiotics: An International Journal >Investigation of antibiotic resistance determinants and virulence factors of uropathogenic Escherichia coli
【24h】

Investigation of antibiotic resistance determinants and virulence factors of uropathogenic Escherichia coli

机译:抗生素抗性抗药性决定因素的调查及尿羟硫育素大肠杆菌的毒力因子

获取原文
获取原文并翻译 | 示例
           

摘要

Multidrug-resistant (MDR) uropathogenic Escherichia coli (UPEC) are prevalent throughout the world resulting in a major public health burden. In this research, we isolated and identified 28 MDR UPEC from one university hospital in China, investigated MDR and pathogenic mechanisms by PCR, including 55 antibiotic resistance determinants (ARDs) genes, 13 genetic markers of mobile genetic elements (MGEs) and 6 virulence factors (VFs) genes. In these isolates, we identified 23 ARDs genes and 6 genetic markers of MGEs that played a key role in MDR phenotypes. In addition, we found 2 VFs genes, hofQ and ompT, which could be associated with pathogenicity and invasiveness of these strains in urinary tract infections (UTIs).
机译:多药物抗性(MDR)尿羟疗法大肠杆菌(UPEC)在全球范围内普遍导致主要的公共卫生负担。 在这项研究中,我们孤立并确定了中国一家大学医院的28名MDR Upec,PCR调查了MDR和致病机制,包括55种抗生素抗性决定因素(ARDS)基因,13个流动遗传元素(MGES)和6种毒力因子的遗传标记 (vfs)基因。 在这些分离株中,我们确定了23个ARDS基因和6种濒危标志物在MDR表型中发挥了关键作用。 此外,我们发现2 vfs基因,Hofq和ompt,其可能与泌尿道感染(UTI)中这些菌株的致病性和侵袭性相关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号