Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II-Invention of afidopyropen

Goto Kimihiko; Horikoshi Ryo; Mitomi Masaaki; Oyama Kazuhiko; Hirose Tomoyasu; Sunazuka Toshiaki; Omura Satoshi

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Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II-Invention of afidopyropen

机译：吡啶丙烯衍生物的合成和杀虫效果。 Afidopyropen的第二部分发明

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The synthesis and insecticidal activity of a series of pyripyropene derivatives with cyclopropanecarbonyloxy group(s) at the C-1, C-7 and/or C-11 position(s) were investigated to find novel insecticides. Insecticidal screening of the synthesized PP derivatives revealed that derivative 13, which had cyclopropanecarbonyloxy groups at the C-1 and C-11 positions and a hydroxyl group at the C-7 position, showed the highest insecticidal activity against aphids in laboratory tests. Finally, we selected 13 as a new insecticide candidate for agricultural sucking pests, which is now commercialized under the common name afidopyropen.

机译：研究了C-1，C-7和/或C-11位在C-1，C-7和/或C-11位的环丙基羰基氧基衍生物的一系列吡啶丙烯衍生物的合成和杀虫活性进行研究以寻找新的杀虫剂。合成的PP衍生物的杀虫筛查显示，在C-1和C-11位位置具有环丙烷羰基氧基和C-7位位置的衍生物13显示出对实验室测试中的蚜虫的最高杀虫活性。最后，我们选择了13名农业吸吮害虫的新杀虫剂候选人，现在在逐个遗产的共同名称下商业化。

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来源
《The Journal of Antibiotics: An International Journal》 |2019年第9期|共21页
作者
Goto Kimihiko; Horikoshi Ryo; Mitomi Masaaki; Oyama Kazuhiko; Hirose Tomoyasu; Sunazuka Toshiaki; Omura Satoshi;
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作者单位

Meiji Seika Pharma Co Ltd Agr &

Vet Div Agr &

Vet Res Labs Yokohama Kanagawa Japan;

Meiji Seika Pharma Co Ltd Agr &

Vet Div Agr &

Vet Res Labs Yokohama Kanagawa Japan;

Meiji Seika Pharma Co Ltd Agr &

Vet Div Agr &

Vet Res Labs Yokohama Kanagawa Japan;

Meiji Seika Pharma Co Ltd Agr &

Vet Div Agr &

Vet Res Labs Yokohama Kanagawa Japan;

Kitasato Univ Kitasato Inst Life Sci Grad Sch Infect Control Sci Tokyo Japan;

Kitasato Univ Kitasato Inst Life Sci Grad Sch Infect Control Sci Tokyo Japan;

Kitasato Univ Kitasato Inst Life Sci Grad Sch Infect Control Sci Tokyo Japan;

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原文格式 PDF
正文语种 eng
中图分类药学;
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专利

1. Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II-Invention of afidopyropen [J] . Goto Kimihiko, Horikoshi Ryo, Mitomi Masaaki, The Journal of Antibiotics: An International Journal . 2019,第9期

机译：吡啶丙烯衍生物的合成和杀虫效果。 Afidopyropen的第二部分发明
2. Synthesis of pyripyropene derivatives and their pest-control efficacy [J] . Guro Kimihiko, Horikoshi Ryo, Nakamura Satoshi, Journal of pesticide science . 2019,第3a4期

机译：吡啶丙烯衍生物的合成及其害虫控制效能
3. Synthesis of pyripyropene derivatives and their pest-control efficacy [J] . Kimihiko Goto, Ryo Horikoshi, Satoshi Nakamura, Journal of pesticide science . 2019,第4期

机译：吡啶丙烯衍生物的合成及其害虫对照功效
4. SYNTHESIS, CHARACTERIZATION AND PERFORMANCE ASSESSMENT OF DIMETHYLTRIAZANIUM SALTS -NITROGEN-RICH HYDRAZINE DERIVATIVES. [C] . Chaza Darwich, Valerian Forquet, Guy Jacob International Annual Conference of ICT . 2014

机译：富含二甲基三烷盐 - 富含氢肼衍生物的合成，表征和性能评估。
5. Bed Bug Resistance to Selected Insecticides and Effect of Moisture on Efficacy of Insecticide Dusts Against the Common Bed Bug, Cimex lectularius [D] . Ranabhat, Sabita . 2020

机译：床虫抗杀虫剂和水分对杀虫剂粉尘对常见床虫的影响，Cimex Lectularius
6. Synthesis of pyripyropene derivatives and their pest-control efficacy [O] . Kimihiko Goto, Ryo Horikoshi, Satoshi Nakamura, 2019

机译：吡y烯衍生物的合成及其防治害虫的功效
7. Studies on Insecticides. V. Synthesis of 2-Piperidone Derivatives. [O] . Torizo Takahashi, Kazuo Kariyone 1960

机译：杀虫剂研究。 V. 2-哌啶酮衍生物的合成。

Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II-Invention of afidopyropen

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