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首页> 外文期刊>The Journal of craniofacial surgery >Hemodynamic Assessment with SPY-Indocyanine Green Angiography in Expansion Period: A Study for Expansion Capsule Pressure Optimization
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Hemodynamic Assessment with SPY-Indocyanine Green Angiography in Expansion Period: A Study for Expansion Capsule Pressure Optimization

机译：膨胀时期间谍 - 吲哚菁绿色血管造影的血流动力学评估：膨胀胶囊压力优化研究

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Tissue expansion-related severe complication exists, and the poor blood supply is one of the causes. After decades of negative correlation between capsule pressure and blood flow was verified, the widely recognized expansion capsule pressure is still absent. A prospective randomized controlled trial was performed to explore the optimal expanding capsule pressure. Thirty subjects were randomly divided into 5 groups, received a weekly expanding on 60-, 70-, 80-, 90-, and 100-mm Hg capsule pressure, respectively. All patients achieved 8-week follow-up; hemodynamic assessment by SPY-indocyanine green (ICG) angiography was taken every 2 weeks. Standardized indexes from SPY-ICG angiography were used to assess the blood supply, in which the ratio of ingress rate and the ingress rate of normal skin (IR/NIR) reflects the arterial perfusion level, and the ratio of Engress Rate and IR (ER/IR) indicates the venous reflux level. The expansion-related adverse events during the trial were recorded. The IR/NIR and the ER/IR are both obviously negatively correlated to the capsule pressure of tissue expander (P 0.05, the ER/IR's correlation coefficient=-0.453; the IR/NIR's correlation coefficient=-0.482). The post-expansion IR/NIR increased significantly after 8 weeks of expansion (P 0.05) in 90-mm Hg group. And the post-expansion ER/IR was significantly elevated (P 0.05) in 80 and 90-mmHg groups. There were 2 expansion-related complications reported in 100-mm Hg group, whereas no complication occurred in 4 other lower groups. SPY-ICG angiography is an objective measurement for tissue expansion hemodynamic monitoring. The expanding capsule pressure of 80 to 90mm Hg is a reasonable upper limit.
机译：存在组织膨胀相关的严重并发症，血液供应不良是原因之一。在透析胶囊压力和血流之间的数十年后，仍然存在广泛认可的膨胀胶囊压力。进行预期随机对照试验，探讨最佳的膨胀胶囊压力。将30个受试者随机分为5组，分别在60-，70-，80-，90-和100mm HG胶囊压力下进行每周膨胀。所有患者均达到8周的随访;通过间谍 - 吲哚菁绿（ICG）血管造影每2周进行血流动力学评估。来自Spy-ICG血管造影的标准化指标用于评估血液供应，其中进入率和正常皮肤（IR / NIR）的进入率的比率反映了动脉灌注水平，以及Engress率和IR的比例（ER / IR）表示静脉回流水平。审判期间的扩增相关不良事件。 IR / NIR和ER / IR均明显与组织膨胀机的胶囊压力有明显呈负相关（P 0.05，ER / IR的相关系数= -0.453; IR / NIR的相关系数= -0.482）。在90毫米HG组的膨胀（P 0.05）的8周后，扩增后的IR / NIR显着增加。并且在80和90mmHg组中，扩增后ER / IR显着升高（p 0.05）。在100 mm Hg组中报告了2种膨胀相关的并发症，而4个其他下部群体没有任何并发​​症。 SPY-ICG血管造影是用于组织膨胀血液动力学监测的客观测量。 80至90mm Hg的膨胀胶囊压力是合理的上限。

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