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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Short interpregnancy interval increases the risk of preterm premature rupture of membranes and early delivery
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Short interpregnancy interval increases the risk of preterm premature rupture of membranes and early delivery

机译：短暂的侵袭间隔增加了早产的膜和早期交付的早产破裂的风险

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Objectives: Preterm premature rupture of membranes (PPROM) is a major contributor to overall preterm birth (PTB) rates. A short interpregnancy interval (IPI) is a well-known risk factor for PTB. It is unknown if a short IPI specifically affects the risk of developing PPROM in a subsequent pregnancy. We sought to determine the association between IPI and the risk of PPROM in a subsequent pregnancy. Methods: A retrospective cohort study using the Missouri birth certificate database of singleton births from 2003 to 2013 was conducted. A short IPI (delivery of the prior pregnancy to conception of the index pregnancy) was defined as <6 months. IPI >6 months was categorized into two groups: IPI 7-23 months and IPI >24 months. PPROM was defined as premature rupture of membranes between 16° and 366 weeks. Multivariable logistic regression was conducted to determine the association between IPI and PPROM while controlling for maternal age, race, body mass index (BMI), education level, use of social services (Medicaid insurance, food stamps, or participation in the WIC [Women, Infants, and Children] program), tobacco use, and history of PTB. Secondary outcome included the gestational age at delivery, categorized into five subgroups (<24°, 24~1-28°, 28~1-32°, 32~1-34°, and 34~1-36~6 weeks).
机译：目的：早产的膜（PPROM）过早破裂是总体早产（PTB）率的主要贡献者。短暂的讲义间隔（IPI）是PTB的众所周知的风险因素。如果短IPI特别影响在随后的怀孕中发育PPROM的风险，则是未知的。我们试图确定IPI之间的关联和随后怀孕中PPROM的风险。方法：采用2003年至2013年使用Mistouri出生证明书数据库的回顾性队列研究。简短的IPI（向指数妊娠的概念进行前期妊娠的交付）被定义为<6个月。 IPI> 6个月被分为两组：IPI 7-23个月和IPI> 24个月。 PPROM被定义为16°和366周之间的膜过早破裂。进行多变量的逻辑回归，以确定IPI和PPROM之间的关联，同时控制产妇年龄，种族，体重指数（BMI），教育水平，社会服务的使用（医疗保险，食品券或参与WIC [女性，婴儿和儿童]计划），烟草使用以及PTB的历史。二次结果包括递送的孕龄，分为五个亚组（<24°，24°，24〜1-28°，28〜1-32°，32〜1-34°，34〜1-36〜6周）。

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