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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >The effect of obesity on early fetal growth and pregnancy duration: a cohort study
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The effect of obesity on early fetal growth and pregnancy duration: a cohort study

机译：肥胖对早期胎儿生长和妊娠持续时间的影响：队列研究

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Objective: The objective of this study is to investigate the effect of maternal obesity on fetal size in first- and second-trimester pregnancies and to determine duration of pregnancy as estimated by a variety of methods. Methods: Between 2006 and 2011, a cohort study included (n = 9055) singleton pregnancies that resulted in live birth at Holbaek Hospital in Denmark. This study recorded first- and second-trimester fetal measurements and maternal anthropometry. Characteristics considered included mother's age, parity, height, body mass index (BMI), smoking habits, and sex of child. The correlation between BMI and duration of pregnancy was analyzed by time-to-event analysis and accounted for medical intervention by censoring while correlation of BMI on fetal size was evaluated by multiple regression analysis. Results: Adjusting for maternal and fetal characteristics, BMI was associated with prolonged pregnancy duration (0.20-0.22 d per kg/m~2 (standard error (SE) 0.02)) when using ultrasound and 0.26 d per kg/m~2 (SE: 0.03) when using last menstrual period. With increasing BMI, fetal biometries in first and second trimester were significantly smaller than expected (0.08 mm per kg/m~2 when measured by crown rump length (SE 0.02)). Conclusions: Maternal BMI is correlated to smaller fetal size in early pregnancy and prolongs duration of pregnancy.
机译：目的：本研究的目的是探讨孕产妇肥胖症对孕孕孕中期和第二三个妊娠的胎儿规模，并根据各种方法确定怀孕的持续时间。方法：2006年至2011年间，包括队列研究（n = 9055）单身妊娠，导致在丹麦的Holbaek医院生存。本研究记录了第一节和第二妊娠胎儿测量和母体人体测量。被认为包括母亲的年龄，平等，身高，体重指数（BMI），吸烟习惯和儿童性别的特征。通过对时间分析进行分析BMI与妊娠持续时间的相关性，并通过审查通过审查进行审查，同时通过多元回归分析评估BMI对胎儿大小的相关性。结果：调整孕产妇和胎儿特征，使用超声波和每kg / m〜2的0.26天（SE ：0.03）使用最后一次月经期。随着BMI的增加，第一和第二三个月的胎儿生物测定物质显着小于预期（每kg / m〜2 0.08mm，通过冠臀长度（SE 0.02）测量时）。结论：母体BMI与妊娠早期胎儿大小相关，延长妊娠持续时间。

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