...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Association of Vac A- and Cag A-specific Helicobacter pylori strain infection with spontaneous preterm birth
【24h】

Association of Vac A- and Cag A-specific Helicobacter pylori strain infection with spontaneous preterm birth

机译：VAC A-和CAG A特异性幽门螺杆菌感染与自发早产的关联

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: To better understand the correlation between Helicobacter pylori (H. pylori) seropositivity and spontaneous preterm birth.Materials and methods: A total of 320 pregnant women were classified into two groups: normal control singleton pregnant group (n=264) and singleton spontaneous preterm birth group (n=56). Blood samples were collected at the time of delivery, and the H. pylori IgG, various virulence factors and systemic inflammation status were compared between the two groups.Results: Between the two groups, the serum H. pylori IgG, Cytotoxin-associated agntigen A (Cag A), Vacuolating cytotoxin A (Vac A) significantly increased in spontaneous preterm birth group than in the control group. Also, in preterm group, highly sensitive C-reactive protein (hsCRP) as a systemic inflammatory marker is statistically elevated at inflammatory status range. Whereas in the term pregnant group, hsCRP was normal range even though high incidence of H. pylori IgG seropositivity. Also, in the seropositive group, hsCRP is statistically correlated with H. pylori IgG, Cag A and Vac A.Conclusions: There is an association between the presence of antibodies against H. pylori in maternal serum and the development of preterm birth. Furthermore, serology type of H. pylori with Vac A, Cag A relates to preterm birth even though high H. pylori prevalence rate.
机译：目的：更好地了解幽门螺杆菌（H. pylori）血清阳性和自发早产之间的相关性。材料和方法：将320名孕妇分为两组：正常对照单身怀孕组（n = 264）和单身自发早产出生组（n = 56）。在递送时收集血液样品，在两组之间比较了H.Pylori IgG，各种毒力因子和全身炎症状态。结果：两组之间，血清H.Pylori IgG，细胞毒素相关的Agntigen A （CAG a），真空早产出生组真菌的细胞毒素A（VAC A）显着增加，而不是对照组。此外，在早产儿中，高敏感的C反应蛋白（HSCRP）作为全身炎症标记物在炎症状态范围内统计上升高。虽然在怀孕术语中，即使H.Pylori IgG血清阳性的高发病率，HSCRP也是正常的范围。此外，在血清阳性基质中，HSCRP与H.Pylori IgG，CAG A和VAC A统计学相关：结论：在母体血清中对幽门螺杆菌的抗体存在之间存在关联和早产的发育。此外，即使高H.幽门患病率，CA​​G A与VAC A，CAG A均涉及早产的血星幽门螺杆菌。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号