...
首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Risk factors for spontaneous localized intestinal perforation in the preterm infant
【24h】

Risk factors for spontaneous localized intestinal perforation in the preterm infant

机译:早产儿自发局部肠穿孔的危险因素

获取原文
获取原文并翻译 | 示例
           

摘要

Purpose: The aim of this study was to investigate prenatal and postnatal risk factors for spontaneous intestinal perforation (SIP) in preterm infants. Material and methods: Matched case-control study of 62 preterm infants (matching based on gender, gestational age and birth weight) who developed a SIP over a period of 20 years in a single NICU. Univariate and multivariate logistic regression analysis were performed. Results: Prenatal risk factors were not significantly different between cases and controls. Patients exposed to surfactant and inotropic agents have an increased risk for SIP. No initiation of feeding before development of SIP and IVH > grade 3 were also associated with an increased risk for SIP. In multivariate analysis inotropic agents, lack of initiation of feeding and IVH > grade 3 remained significant risk factors (OR 5.58 (95% Cl 1.14-27.22), 0.29 (95% Cl 0.09-0.88), 15.2 (95% Cl 1.09-211.55) respectively). Conclusions: The study found that patients with SIP are more likely to have been exposed to inotropic agents and to have developed IVH > grade 3. They were also less likely to have been fed. These risk factors most likely reflect the severity of illness of preterm infants and an increased vulnerability for developing SIP.
机译:目的:本研究的目的是探讨早产儿的产前和产前危险因素(SIP)。材料与方法:62个早产儿的匹配病例对照研究(基于性别,孕龄和出生体重的匹配),他在单一Nicu在20年内开发了一个啜饮的啜饮。进行单变量和多变量逻辑回归分析。结果:病例和对照之间的产前风险因素没有显着差异。暴露于表面活性剂和渗透剂的患者增加了SIP的风险增加。在SIP和IVH> 3级开发前没有喂养的开始也与SIP的增加的风险增加。在多变量分析的各渗透剂中,饲料和IVH> 3级的缺乏引发仍然存在显着的风险因素(或5.58(95%Cl 1.14-27.22),0.29(95%Cl 0.09-0.88),15.2(95%Cl 1.09-211.55 ) 分别)。结论:该研究发现,SIP的患者更容易暴露于官能药物,并开发IVH>等级3.它们也不太可能喂食。这些风险因素最有可能反映早产儿疾病的严重程度,并增加脆弱性的脆弱性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号