...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Utility of hepatobiliary scintigraphy in diagnosing or excluding biliary atresia in premature neonates and full-term infants with conjugated hyperbilirubinemia who received parenteral nutrition
【24h】

Utility of hepatobiliary scintigraphy in diagnosing or excluding biliary atresia in premature neonates and full-term infants with conjugated hyperbilirubinemia who received parenteral nutrition

机译：肝胆闪烁扫描在诊断或排除胆道休息室的早产儿和患有肠外营养的共轭高胆管血症的全术婴儿

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: Hepatobiliary scintigraphy (HBS) is used to aid in the diagnosis of Biliary Atresia in full-term infants with conjugated hyperbilirubinemia. There is little information on the utility of the HBS in premature infants with conjugated hyperbilirubinemia and infants with parenteral nutrition associated cholestasis (PNAC). The purpose of this study is to assess the utility of HBS in differentiating Biliary Atresia and PNAC in premature neonates and full-term infants who received parenteral nutrition (PN).Materials and methods: Retrospective data collection and analysis on infants who developed conjugated hyperbilirubinemia and had HBS performed during their stay at level IV neonatal intensive care unit between 2005 and 2015.Results: A total of 20 patients with exposure to PN had HBS; two patients were confirmed to have Biliary Atresia. There were no statistically significant differences between patients with Biliary Atresia versus PNAC in demographics, days on PN, or gamma glutamyl-transferase levels. Stool color was statistically significantly different between the two groups; patients with Biliary Atresia had acholic stools more consistently than patients without Biliary Atresia. HBS had 100% sensitivity, 17% specificity, positive-predictive value of 12%, and a negative-predictive value (NPV) of 100%.Conclusions: These data indicate that the ability of HBS to aid in diagnosing Biliary Atresia is poor in a population of preterm neonates and full-term infants with PNAC. Although there is 100% sensitivity, the poor specificity (17%) should be acknowledged when utilizing HBS to diagnose Biliary Atresia in this vulnerable patient population. NPV of 100% is helpful in ruling out Biliary Atresia in this population.
机译：目的：肝胆闪烁扫描（HBS）用于帮助诊断患有共轭的高胆管血症的全术婴儿的胆道闭锁。有关HBS在早产儿的效用的信息很少，具有共轭的高胆红素血症和患有肠胃外营养相关的胆汁淤积（PNAC）的婴儿。本研究的目的是评估HBS在将胆道休息和PNAC中的早产儿和全术婴儿进行分化为肠外营养（PN）的全长婴儿。材料和方法：回顾性数据收集和开发共轭高胆红素血症的婴儿的分析在2005年至2015年间停留在静脉内新生儿重症监护病房期间进行了HBS。结果：共有20名暴露于PN的患者HBS;两名患者被证实有胆道腹部腹部。胆道患者与人口统计学中的pNAc患者没有统计学显着差异，pN的天数，或γ谷氨酸转移酶水平。两组之间的大便颜色在统计学上有明显不同;胆道腹部患者比没有胆道休息的患者更符合持胆量。 HBS具有100％的灵敏度，17％的特异性，阳性预测值12％，负预测值（NPV）为100％。链接：这些数据表明HBS帮助诊断胆道闭锁的能力差早产儿和患有PNAC的全年婴儿的人口。虽然有100％的灵敏度，但在利用HBS在这种脆弱的患者人群中诊断胆道腹部患者时​​，应承认差的特异性（17％）。 100％的NPV有助于在这群人群中统治胆道休息。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号