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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Bisphenol A and adverse pregnancy outcomes: a systematic review of the literature
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Bisphenol A and adverse pregnancy outcomes: a systematic review of the literature

机译：双酚A和不良妊娠结果：对文献的系统审查

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Purpose: Bisphenol A is a chemical compound related to adverse maternal and neonatal outcomes. The purpose of the present systematic review is to summarize the current knowledge in the field.Materials and methods: We systematically searched the Medline (1966-2017), Scopus (2004-2017), Clinicaltrials.gov (2008-2017), Cochrane Central Register of Controlled Trials CENTRAL (1999-2017) databases.Results: Thirty-five studies were included in the present systematic review. According to our findings, BPA has a direct negative impact on maternal, fetal, and neonatal outcomes, including birthweight, rates of preterm birth, developmental defects, and recurrent miscarriage. Data in the field of preeclampsia and gestational diabetes mellitus remain inconclusive because current research is very limited.Conclusions: BPA exposure during pregnancy can result in significant antenatal pathology; hence, occupational exposure should be at least discouraged during this period. However, cross-sectional studies in the field that would assess the levels of exposure at timely intervals are still lacking, therefore, the actual impact of BPA remains unclear.
机译：目的：双酚A是与不良母体和新生儿结果有关的化学化合物。目前系统审查的目的是总结现场中的目前知识。材料和方法：我们系统地搜索了Medline（1966-2017），Scopus（2004-2017），ClicinTrials.gov（2008-2017），Cochrane Central受控试验登记中心（1999-2017）数据库。结果：本系统审查中包含三十五项研究。根据我们的研究结果，BPA对孕产妇，胎儿和新生儿结果具有直接的负面影响，包括出生体重，早产率，发育缺陷和经常流产。预革兰和妊娠期糖尿病领域的数据仍然不确定，因为目前的研究非常有限。结论：怀孕期间的BPA暴露可能导致显着的产前病变;因此，在此期间，应至少气馁职业暴露。然而，将在及时评估曝光程度的领域的横截面研究仍然缺乏，因此，BPA的实际影响仍不清楚。

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