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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Risk factors for fatality in amniotic fluid embolism: a systematic review and analysis of a data pool
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Risk factors for fatality in amniotic fluid embolism: a systematic review and analysis of a data pool

机译：羊水栓塞致命风险因素：数据池的系统审查与分析

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Purpose: Investigating risk factors for amniotic fluid embolism (AFE)-induced fatality.Methods: A systematic review of cases of AFE available on PubMed, Scielo, Scopus and AJOL databases that occurred from 1990 to 2015 was carried out. After careful reading of titles, abstracts and full texts, case reports of AFE were reviewed. Risk factors for AFE were considered as independent variables in logistic regression models. The first model was built on the whole data pool. The second model was built on typical cases of AFE, according to the classical triad of symptoms (heart, lungs, coagulopathy). The dependent variable was fatality in both models.Results: 177 cases of AFE were assessed in the first model, while 121 typical cases of AFE were assessed in the second model. Among typical cases of AFE, only oxytocin infusion during labour increases the likelihood of death (odds ratio 2.890, 95% confidence interval 1.166-7.164, p=0.022). No risk factors for fatality were found in the whole data pool.Conclusions: Further research on national registries should focus on the behaviour of oxytocin infusion during labour in AFE cases.
机译：目的：研究羊水栓塞（AFE）的危险因素 - 诱导的死亡。方法：1990年至2015年发生的PubMed，Scielo，Scopus和AJOL数据库中提供的AFE案例的系统审查。经过仔细阅读标题，摘要和全文后，审查了AFE的案例报告。 AFE的危险因素被认为是Logistic回归模型中的独立变量。第一个模型是在整个数据池上构建的。根据症状的经典三态（心脏，肺，凝血病），建立了第二种模型。依赖变量在两种模型中都是致命性。结果：在第一款模型中评估了177例AFE，而在第二种模型中评估了121例AFE病例。在AFE的典型情况中，劳动期间的催产素输注增加了死亡的可能性（差距2.890,95％置信区间1.166-7.164，P = 0.022）。在整个数据池中没有发现死亡的危险因素。结论：关于国家注册管理机构的进一步研究应关注催产素输注在劳动期间的行为。

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