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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Is preterm delivery an independent risk factor for long-term maternal kidney disease?
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Is preterm delivery an independent risk factor for long-term maternal kidney disease?

机译：早产是长期产妇肾病的独立危险因素吗？

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Objective: To investigate whether women who had a preterm delivery (PTD) are at an increased risk of subsequent long term maternal kidney disease.Study design: A population-based study compared the incidence of long-term maternal kidney disease in a cohort of women with and without previous PTD. Deliveries occurred during a 25 years period, with a mean follow-up duration of 11.2 years.Results: Of 99 338 deliveries of women, 16 364 (16.4%) occurred in patients who had at least one PTD. A significant dose response was found between the number of previous PTDs and the gestational age at birth of the PTDs and future risk for renal-related hospitalizations. Patients with either spontaneous or indicated PTD had higher rates of renal-related hospitalizations (0.2% versus 0.1% OR=2.6; 95%CI: 1.7-3.9, p <0.001 and 0.5% versus 0.2% OR 3.41; 95%CI: 1.7-6.5, p <0.001, respectively). In a Cox proportional hazards model, PTD was independently associated with long-term maternal renal-related hospitalizations.Conclusions: PTD is an independent risk factor for long-term maternal kidney disease.
机译：目的：探讨患有早产的女性是否存在于随后的长期孕产妇肾病的风险增加。研究：基于人群的研究比较了女性队列的长期母亲肾脏疾病的发生率没有以前的PTD。交货发生在25年期间，其平均随访期为11.2年。结果：99 338个妇女交付，1664名（16.4％）发生至少一个PTD的患者。在PTD诞生时之前PTD的数量和肾脏相关住院的未来风险之间存在显着的剂量反应。具有自发性或表明PTD的患者具有较高的肾相关住院率（0.2％，而0.1％或= 2.6; 95％CI：1.7-3.9，P <0.001和0.5％，对0.2％或3.41; 95％CI：1.7 -6.5，p <0.001分别）。在COX比例危险模型中，PTD与长期妇幼的肾相关住院相关有关。结论：PTD是长期孕产妇肾病的独立危险因素。

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