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首页> 外文期刊>The Journal of Comparative Neurology >Cytoarchitecture and myeloarchitecture of the entorhinal cortex of the common marmoset monkey ( Callithrix jacchus ) Callithrix jacchus Callithrix jacchus )
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Cytoarchitecture and myeloarchitecture of the entorhinal cortex of the common marmoset monkey ( Callithrix jacchus ) Callithrix jacchus Callithrix jacchus )

机译：CytoArchitecture和Myelo建筑的普通Marmoset猴子（Callithrix jacchus）Callithrix Jacchus Callithrix Jacchus）

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Abstract The entorhinal cortex (EC) is associated with impaired cognitive function such as in the case of Alzheimer's disease, Parkinson's disease and Huntington's disease. The present study provides a detailed analysis of the cytoarchitectural and myeloarchitectural organization of the EC in the common marmoset Callithrix jacchus . Data were collected using Nissl and fiber stained preparations, supplemented with acetylcholinesterase and parvalbumin immunohistochemistry. The EC layers and subfields in the marmoset seem to be architectonically similar to those that have been proposed in nonhuman primates and humans to date; however, slight differences could be revealed using the present techniques. Throughout its rostrocaudal length, the entorhinal cortex presents a clear six‐layered pattern. The entorhinal cortex is divided into six fields, named mainly in accordance to their rostrocaudal and mediolateral positions. At rostral levels, the neurons tend to be organized in patches that are surrounded by large, thick, radially oriented bundles of fibers, and the deep layers are poorly developed. At caudal levels, the divisions are more laminated in appearance. AChE staining at the borders of adjacent fields are consistent with the changes in layering revealed in Nissl‐stained sections, of which the lateral regions of the EC display denser AChE staining than that of the medial banks. PV immunoreactivity was found in the labeled somata, dendrites, and axons in all layers and subdivisions. Additionally, we distinguished three subtypes of PV‐immunoreactive neurons: multipolar, bipolar and spherical‐shaped neurons, based on the shape of the somata and the disposition of the dendrites.
机译：摘要Entorhinal Cortex（EC）与认知功能受损相关，例如在阿尔茨海默病，帕金森病和亨廷顿氏病的情况下。本研究详细分析了普通的Marmoset Callithrix Jacchus中EC的细胞建筑和Myelo建筑组织。使用NISSL和纤维染色制剂收集数据，所述制剂补充有乙酰胆碱酯酶和帕瓦仑免疫组化。 Marmoset中的EC层和子场似乎是与迄今为止在非人类灵长类动物和人类中提出的那些相似的建立类似的;但是，可以使用本技术揭示轻微的差异。整个rostrocaudal长度，Entorhinal Cortex呈现出明确的六层图案。 Entorhinal Cortex分为六个领域，主要根据其rostrocaudal和Mediolateral位置命名。在rostral水平下，神经元倾向于在由大，厚的径向取向束纤维包围的斑块中组织，并且深层显得不佳。在尾部，部门的外表更加层次。在相邻场的边界处的疼痛染色与NISSL染色部分中揭示的分层的变化一致，其中EC显示器的横向区域比内侧堤的染色效果。在标记的Somata，Dendrites和轴突中发现了PV免疫反应性。另外，基于SOMATA的形状和树突的布置，我们分析了三种PV-免疫反应性神经元：多极，双极和球形神经元的亚型。

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