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Immune Checkpoint Imaging in Oncology: A Game Changer Toward Personalized Immunotherapy?

机译:免疫检查点成像在肿瘤学中:对个性化免疫疗法的游戏变频器?

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摘要

Immune checkpoint blockade represents a promising approach in oncology, showing antitumor activities in various cancers. However, although being generally far better tolerated than classic cytotoxic chemotherapy, this treatment, too, may be accompanied by con-siderable side effects and not all patients benefit equally. Therefore, careful patient selection and monitoring of the treatment response is mandatory. At present, checkpoint-specific molecular imaging is being increasingly investigated as a tool for patient selection and response evaluation. Here, an overview of the current developments in immune checkpoint imaging is provided.
机译:免疫检查点封闭代表了肿瘤学中有希望的方法,显示各种癌症中的抗肿瘤活性。 然而,虽然通常比经典细胞毒性化学疗法更好的耐受性,但这种处理也可以伴有Con-Siderable的副作用,而不是所有患者同样受益。 因此,仔细患者的选择和监测治疗响应是强制性的。 目前,越来越多地研究了特异性分子成像作为患者选择和响应评估的工具。 这里,提供了免疫检查点成像的当前发展的概述。

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