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首页> 外文期刊>The American Biology Teacher: Journal of the National Association of Biology Teachers >Using Shapes & Codes to Teach the Central Dogma of Molecular Biology: A Hands-On Inquiry-Based Activity
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Using Shapes & Codes to Teach the Central Dogma of Molecular Biology: A Hands-On Inquiry-Based Activity

机译:使用形状和代码教导分子生物学中央教条:一项动手查询的活动

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摘要

The central dogma of molecular biology is key to understanding the relationship between genotype and phenotype, although it remains a challenging concept to teach and learn. We describe an activity sequence that engages high school students directly in modeling the major processes of protein synthesis using the major components of translation. Students use a simple system of codes to generate paper chains, allowing them to learn why codons are three nucleotides in length, the purpose of start and stop codons, the importance of the promoter region, and how to use the genetic code. Furthermore, students actively derive solutions to the problems that cells face during translation, make connections between genotype and phenotype, and begin to recognize the results of mutations. This introductory activity can be used as an interactive means to support students as they learn the details of translation and molecular genetics.
机译:分子生物学的中央教条是了解基因型和表型之间关系的关键,尽管它仍然是教学和学习的具有挑战性的概念。 我们描述了一种活动序列,可以使用翻译主要成分直接与高中生直接造型蛋白质合成的主要过程。 学生使用简单的代码系统来生成纸链,让他们了解为什么密码子的长度是三个核苷酸,开始和止扰密码子的目的,启动子区域的重要性以及如何使用遗传密码。 此外,学生积极推导出对平移期间面临的问题的解决方案,在基因型和表型之间进行连接,并开始识别突变的结果。 该介绍活动可以用作支持学生的互动手段,因为他们了解翻译和分子遗传学的细节。

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