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首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >Appropriate Use of Ceftriaxone in the Emergency Department of a Veteran’s Health Care System
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Appropriate Use of Ceftriaxone in the Emergency Department of a Veteran’s Health Care System

机译:适当地使用Ceftriaxone在退伍军人的医疗保健系统的急诊部门

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Background: Ceftriaxone is a third-generation cephalosporin commonly utilized as an empiric antibiotic treatment option in the emergency department (ED). Overuse can lead to decreased susceptibility and emergence of multidrug-resistant pathogens, increased costs, and unnecessary adverse effects. Objective: The purpose of this project was to determine the appropriateness of ceftriaxone usage in the ED of a veteran’s health care system. Methods: This retrospective chart review included all veterans who received at least one dose of ceftriaxone in the ED between June 1, 2014, and June 1, 2015. The primary outcome was the percentage of appropriate ceftriaxone use. Usage appropriateness was determined on a case-by-case basis by examining current published guidelines and local recommendations based on the institutional antibiogram. Results: Ceftriaxone was prescribed for a wide variety of indications and was determined to be inappropriately prescribed in 164 patients (53%). The most common reason for inappropriate prescribing was lack of a first-line indication for ceftriaxone (64%). Only 120 patients (38.5%) exhibited systemic signs of infection based on vital signs and laboratory parameters, and 25 patients (8%) likely did not require antibiotic therapy at all. Conclusions: Ceftriaxone was used inappropriately in more than half of the patients who received the drug in the ED. The literature on the prescribing habits for ceftriaxone is limited in the United States, but these results are similar to studies conducted in other countries. Attempts should be made to educate prescribers on appropriate indications for the use of ceftriaxone.
机译:背景:Ceftriaxone是急诊部(ED)中常用为经验抗生素治疗方案的第三代头孢菌素。过度使用可能导致多药物抗性病原体的易感性和出现,增加成本和不必要的不​​利影响。目的:该项目的目的是确定RETAN的医疗保健系统ED中CEFTRIAXONE使用的适当性。方法:此次回顾性图表审查包括在2014年6月1日至2015年6月1日期间在ED中收到至少一剂Ceftriaxone的退伍军人。主要结果是适当的头孢曲松使用的百分比。通过根据机构抗诊断审查当前公布的指南和本地建议,根据案例确定使用适当性。结果:Ceftriaxone针对各种适应症规定,并确定在164名患者(53%)中不恰当地处方。不适当的处方的最常见原因是头孢曲松的一线指示(64%)。只有120名患者(38.5%)表现出基于生命体征和实验室参数的系统性感染迹象,25名患者(8%)可能根本不需要抗生素治疗。结论:在ED中收到药物的一半以上的患者中使用Ceftriaxone不恰当地使用。关于Ceftriaxone的处方习惯的文献在美国有限,但这些结果与其他国家进行的研究类似。应在适当的适当适应症的使用中教育规定的尝试。

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