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首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >An Evaluation of Pharmacist-Led Interventions for Inpatient HIV-Related Medication Errors
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An Evaluation of Pharmacist-Led Interventions for Inpatient HIV-Related Medication Errors

机译：对病例艾滋病毒相关药物误差的药剂师LED干预评估

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Background: Inpatient HIV-related medication errors occur in up to 86% of patients. Objective: To evaluate the number of antiretroviral therapy (ART)- and opportunistic infection (Ol)-related medication errors following the implementation of pharmacist-directed interventions. Methods: This quasi-experiment assessed adult patients with HIV who received ART, Ol prophylaxis, or both from December I, 2014, to February 28, 2017 (pre-intervention) or December I, 2017, to February 28, 2018 (post-intervention). Pre-intervention patients were assessed retrospectively; verbal and written education were provided (intervention); prospective audit and feedback was conducted for post-intervention patients. The primary outcome was rate of ART errors between groups. Secondary outcomes included rate of Ol errors, time to resolution of ART and Ol errors, types of errors, and rate of recommendation acceptance. Results: Sixty-seven patients were included in each group. ART errors occurred in 44.8% and 32.8% (P = . 156), respectively. Ol prophylaxis errors occurred in 11.9% versus 9% (P = .572), respectively. Medication omission decreased significantly in the post-intervention group (31.3% vs 11.9%; P = .006). Pharmacist-based interventions increased in the post-intervention group (6.3% vs 52.9%; P = .001). No statistical difference was found in time to error resolution (72 vs 48 hours; P = .123), but errors resolved during admission significantly increased (50% vs 86.8%; P < .001). No difference was found in rate of intervention acceptance (100% vs 97%). Conclusion and Relevance: ART and Ol prophylaxis errors resolved a day faster in the pharmacist-led, post-intervention period, and there was a trend toward error reduction. Future interventions should target prescribing errors on admission using follow-up education and evaluation of medication reconciliation practices in HIV-infected patients.
机译：背景：Inpatient HIV相关药物错误发生在高达86％的患者中。目的：评价抗逆转录病毒治疗（艺术） - 和机遇主义感染（OL） - 实施后药剂指导干预措施。方法：该准实验评估了在2017年2月28日（2017年12月28日至2017年12月28日至2017年2月28日至2018年2月28日）的艾滋病毒患者的成人患者干涉）。介绍性患者进行了回顾性评估;提供口头和书面教育（干预）;潜在审计和反馈是针对干预后患者进行的。主要结果是组之间的艺术误差率。次要结果包括OL错误的速率，解决艺术和OL错误的时间，错误的类型，以及推荐率接受。结果：每组六十七名患者。艺术错误分别在44.8％和32.8％（P = 156）中发生。 ol预防误差分别发生在11.9％（p = .572）中发生。后介入组中的药物遗漏显着下降（31.3％Vs 11.9％; p = .006）。后干预课基的药剂师的干预措施增加（6.3％Vs 52.9％; P = .001）。没有及时发现统计差异来误差分辨率（72 vs 48小时; p = .123），但在入学期间解决的错误显着增加（50％vs 86.8％; p <.001）。干预验收率没有差异（100％vs 97％）。结论和相关性：艺术和初预防误差在药剂师LED，干预后期的速度更快地解决了一天，并且减少了误差的趋势。未来的干预措施应使用艾滋病毒感染患者的后续教育和药物和解实践的后续教育和评估来瞄准预订错误。

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