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首页> 外文期刊>AIDS care. >Social and behavioural factors associated with HIV seroconversion in homosexual men attending a central London STD clinic: a feasibility study.
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Social and behavioural factors associated with HIV seroconversion in homosexual men attending a central London STD clinic: a feasibility study.

机译：与伦敦市中心性病门诊的同性恋男性中HIV血清转化相关的社会和行为因素：一项可行性研究。

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An unmatched retrospective case control study was conducted to test the feasibility of investigating social and behavioural factors which may have contributed to recent HIV seroconversion in a group of homosexual men. Participants, recruited from a London sexually transmitted disease (STD) clinic, were sexually active and had had a negative HIV test with a subsequent test (positive (cases) or negative (controls)) within three to 15 months. Twenty cases and 22 controls were recruited between February and October 1995. There was no difference between cases and controls in: the number of regular or casual sexual partners, the proportion who were unaware of their regular partners' serostatus (cases 60%, controls 59%), or the proportion who had known HIV-positive regular partners (cases 20%, controls 23%). A significant difference in sexual behaviour was found only when the HIV status of partners, if known, was taken into account: cases were more likely than controls to have had unprotected receptive anal intercourse with a partner not known to be HIV-negative (OR = 5.5, CI = 1.15-29.50). Fifty per cent of the cases and 27% of the controls acquired acute STDs between the two HIV tests. All participants achieved high self-efficacy scores, but the controls believed their peers placed a greater value on safer sex. Cases cited emotional issues and the use of drugs and alcohol as contributing to their seroconversion, whereas controls cited a commitment to safer sex and the avoidance of high-risk situations as contributing to their remaining HIV-negative. The results illustrate the importance of acknowledging the concept of 'negotiated safety' in studies of sexual behaviour; seroconversion was only associated with unprotected sex with a partner not known to be HIV-negative. Despite high self-efficacy scores, indicating the skills to negotiate safer sex, high levels of unsafe anal intercourse were reported. Differences between cases and controls included the importance of safer sex, periods of emotional vulnerability, influence of peers and the appropriate use of condoms. There is a need for these results to be confirmed in a larger and more powerful study.
机译：进行了一项无与伦比的回顾性病例对照研究，以检验调查社会和行为因素的可行性，这些因素可能导致最近一群同性恋男子的艾滋病毒血清转变。从伦敦性传播疾病（STD）诊所招募的参与者性活跃，在3到15个月内HIV阴性，随后进行了阳性（例）或阴性（对照）测试。在1995年2月至10月之间招募了20个病例和22个对照。病例与对照之间没有差异：经常性或临时性伴侣的数量，不知道其定期伴侣血清状况的比例（病例60％，对照59 ％），或已知有HIV阳性定期伴侣的比例（病例20％，对照23％）。仅在考虑了伴侣的艾滋病毒状况（如果已知）的情况下，发现性行为上的显着差异：病例比对照组更容易与未知HIV阴性的伴侣进行未经保护的肛交（OR = 5.5，CI ＝ 1.15-29.50）。在两次HIV检测之间，有50％的病例和27％的对照获得了急性性病。所有参与者的自我效能得分都很高，但对照组认为他们的同龄人更重视安全性行为。案例中提到情绪问题以及使用毒品和酒精对他们的血清转化有帮助，而对照组则提到致力于更安全的性行为和避免高危情况，这是导致他们仍为艾滋病毒阴性的原因。结果表明，在性行为研究中承认“协商的安全性”概念的重要性。血清转化仅与未受保护的性行为有关，而该性行为与一个艾滋病毒阴性的伴侣无关。尽管自我效能感得分高，表明了进行更安全性行为的技巧，但仍报告了高水平的不安全肛交。病例与对照之间的差异包括安全性行为的重要性，情绪脆弱时期，同伴的影响以及安全套的适当使用。这些结果需要在更大，更强大的研究中得到证实。

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