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首页> 外文期刊>AIDS care. >Economic and quality of life outcomes of antiretroviral therapy for HIV/AIDS in developing countries: a systematic literature review.
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Economic and quality of life outcomes of antiretroviral therapy for HIV/AIDS in developing countries: a systematic literature review.

机译：发展中国家针对艾滋病毒/艾滋病的抗逆转录病毒疗法的经济和生活质量结果：系统文献综述。

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The impacts of antiretroviral therapy (ART) on quality of life, mental health, labor productivity, and economic wellbeing for people living with HIV/AIDS in developing countries are only beginning to be measured. We conducted a systematic literature review to analyze the effect of ART on these economic and quality of life indicators in developing countries and assess the state of research on these topics. We searched Ovid/Medline, PubMed, Psych Info, Web of Science, Google Scholar, and the abstract database of the International AIDS Society Conference and the Conference on Retroviruses and Opportunistic Infections. Both qualitative and quantitative studies were included, as were peer-reviewed articles, gray literature, and conference abstracts and presentations. Findings are reported from 21 publications, including 14 full-length articles, six abstracts, and one presentation (representing 16 studies). Compared to HIV-positive patients not yet on treatment, patients on ART reported significant improvements in physical, emotional and mental health, and daily function. Work performance improved and absenteeism decreased, with the most dramatic changes occurring in the first three months of treatment and then leveling off. Little research has been done on the impact of ART on household wellbeing, with modest changes in child and family wellbeing within households where adults are receiving ART reportrd so far. Most studies from developing countries have not yet assessed economic and quality of life outcomes of therapy beyond the first year; therefore, longitudinal outcomes are still unknown. Findings were limited geographically, with an emphasis on sub-Saharan Africa and adult treatment. As ART roll out extends throughout high HIV prevalence, low-resource countries and is sustained over years and decades, research on pediatric and differential gender economic and quality of life outcomes will become increasingly urgent, as will systematic evaluation of ART programs.
机译：抗逆转录病毒疗法（ART）对发展中国家艾滋病毒/艾滋病患者的生活质量，心理健康，劳动生产率和经济福祉的影响才刚刚开始衡量。我们进行了系统的文献综述，以分析抗病毒治疗对发展中国家这些经济和生活质量指标的影响，并评估这些主题的研究状况。我们搜索了Ovid / Medline，PubMed，心理信息，Web of Science，Google Scholar和国际艾滋病协会会议以及逆转录病毒和机会感染会议的摘要数据库。定性和定量研究都包括在内，同行评议的文章，灰色文献以及会议摘要和介绍也都包括在内。报告的发现来自21份出版物，包括14篇全长文章，6篇摘要和1篇介绍（代表16项研究）。与尚未接受治疗的HIV阳性患者相比，接受ART治疗的患者报告其身体，情绪和心理健康以及日常功能得到了显着改善。工作表现得到改善，旷工减少，最显着的变化发生在治疗的前三个月，然后趋于平稳。关于抗逆转录病毒疗法对家庭福祉的影响的研究很少，迄今为止，成年人接受抗逆转录病毒治疗的家庭中儿童和家庭幸福的变化不大。发展中国家的大多数研究都未评估第一年后的经济和生活质量。因此，纵向结果仍然未知。结果在地理上受到限制，重点是撒哈拉以南非洲地区和成人待遇。随着抗病毒治疗的推广遍及艾滋病高流行，资源贫乏的国家，并持续了数十年之久，有关儿科和性别差异经济和生活质量结果的研究将变得越来越紧迫，对抗病毒治疗计划的系统评估也将越来越迫切。

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