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Sexual Quality of Life and Association With HIV and Sexually Transmitted Infections Among a Cohort of Heterosexual Couples in Kenya

机译:在肯尼亚的异性恋夫妇队列中的生活质量和艾滋病毒和性传播感染

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IntroductionSexual quality of life (SQoL) is a critical component of sexual health and is understudied in Sub-Saharan African settings with endemic HIV and sexually transmitted infection (STI). AimWe sought to assess SQoL among heterosexual couples in Kisumu, Kenya, and how this was associated with HIV status, STIs, and sexual practices. MethodsThis was a prospective cohort study of community-recruited couples. SQoL, HIV status, herpes simplex virus (HSV)-2 status, bacterial vaginosis (BV), sexual practices, and sociodemographics were measured at baseline, 6 months, and 12 months. Multivariable linear regression with random intercept was fitted separately for females and males, accounting for partner characteristics. Main Outcome MeasureSQoL was assessed with an 18-item female and 11-item male survey. ResultsFrom April 2014 through July 2016, 252 couples were enrolled, and followed up through September 2017. At baseline, women were median age 23 years, 10% HIV positive, 53% HSV-2 seropositive, and 22% with BV. At baseline men were median age 26 years, 12% HIV positive, 47% HSV-2 seropositive, and 56% circumcised. Mean SQoL was higher for men (88) than women (78), with consistent scores over time. In multivariable analysis (P< .05 each), SQoL Questionnaire—Female (SQoL-F) score was reduced with: male partner report that sex felt rougher than he would have liked (9.5-point decrease), female HSV-2 seropositivity (5.15-point decrease), female reported having dry vaginal sex (5.27-point decrease); among women with BV, SQoL-F score declined with recent sexual activity (8.27-point decrease) and increasing age (0.75-point decrease per 1 year increase in age). Age and recent sex did not affect SQoL-F for women without BV. SQoL Questionnaire—Male score was decreased 4.99 points if male was employed, 4.52 points if male reported multiple recent sex partners, and 29.5 points for HIV positive men whose female partner reported having sex when not in the mood. Men’s SQoL increased by 0.84 points for each 1-U increase in female partner body mass index and 17.6 points for HIV positive men whose female partner reported recent sex with him. Clinical ImplicationsWithin sexual partnerships, men had greater SQoL than women, and the adverse impact of BV and STIs on SQoL was greater for women than men. Strength & LimitationsResearch is needed to ensure relevant domains are measured in settings where measure of SQoL has not been validated, along with robust measures of physiologic and psychologic correlates. ConclusionMore attention to SQoL as an outcome may strengthen interventions aimed at preventing HIV and STIs and improving sexual health holistically.Mehta SD, Nordgren RK, Agingu W, et?al. Sexual Quality of Life and Association With HIV and Sexually Transmitted Infections Among a Cohort of Heterosexual Couples in Kenya. J Sex Med 2018;15:1446–1455.
机译:引入生活质量(SQOL)是性健康的关键组成部分,在撒哈拉以南非洲环境中被描述,具有特有的艾滋病毒和性传播感染(STI)。 AIMWE试图评估Kisumu,Kenya的异性恋夫妇中的SQOL,以及如何与HIV状态,STI和性行为有关。方法旨在为社区招募的夫妇进行了一个潜在的队列研究。 SQOL,HIV状态,单纯疱疹病毒(HSV)-2状态,细菌性阴道病(BV),性行法,6个月和12个月。随机拦截的多变量线性回归分别适用于女性和男性,占合作伙伴特征。通过18项女性和11件男性调查评估主要结果措施。结果从2016年4月至2016年7月,252夫妇注册,并在2017年9月举行。在基线,女性是23岁的中位数,10%HIV阳性,53%HSV-2血清阳性,22%,BV 22%。在基线男性中位数26岁,艾滋病毒阳性12%,HSV-2血清阳性47%,割礼56%。男性(88)的平均SQOL比女性(78)更高,随着时间的推移一致得分一致。在多变量分析(每个P <.05)中,SQOL调查问卷 - 女性(SQOL-F)得分减少:男性伴侣报告称,性别感到比他所喜好的(9.5点减少),女性HSV-2血清阳性( 5.15点减少),女性报告的阴道性(5.27点减少);在BV的女性中,SQOL-F分数随着最近的性活动(8.27点降低)和增加的年龄(每1年增加0.75点)。年龄和最近的性别对没有BV的女性没有影响SQOL-F.如果采用男性,SQOL调查问卷 - 男性评分减少了4.99点,如果男性报告多年期末性伙伴,29.5分给艾滋病毒阳性男性的29.5分,他的女性伴侣在心情中出现性行为。男性SQOL增加了每1-U增加0.84点,女性伴侣体重指数和艾滋病毒阳性男性的17.6分,他们的女性伴侣报告近期与他性发生性关系。临床暗示性伙伴关系,男性的SQOL比女性更大,而BV和STI对SQOL的不利影响比男性更大。需要强度和限制服务以确保在尚未验证SQOL的测量的情况下测量相关域,以及生理和心理学的稳健措施。结论越来越多的SQOL作为一个结果,可能加强旨在预防艾滋病毒和STI的干预措施,改善性健康,即全球性健康.Mehta SD,Nordgren RK,Agingu W,Et?Al。肯尼亚异性恋夫妇队列生活质量与艾滋病毒和性传播感染。 J SEX MED 2018; 15:1446-1455。

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