...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>AIDS care. >Commercial lubricant use among HIV-negative men who have sex with men in Los Angeles: Implications for the development of rectal microbicides for HIV prevention
【24h】

Commercial lubricant use among HIV-negative men who have sex with men in Los Angeles: Implications for the development of rectal microbicides for HIV prevention

机译：在洛杉矶与男性发生性关系的艾滋病毒阴性男性中使用商业润滑剂：对预防艾滋病毒的直肠杀菌剂的发展具有影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To inform the development and assess potential use of rectal microbicide gels for HIV prevention among men who have sex with men (MSM), we examined the dynamics and contexts of commercial lubricant use during receptive anal intercourse (RAI) within this population. From 2007 to 2010, 168 HIV-negative MSM living in Los Angeles who practice RAI completed computer-assisted self-interviews, which collected information on their last sexual event with ≤3 recent partners, at baseline, three months, and one-year study visits. Logistic generalized linear mixed models were used to identify individual- and sexual event-level characteristics associated with commercial lubricant use during RAI at the last sexual event within 421 partnerships reported by participants over the course of follow-up. During RAI at their last sexual event, 57% of partnerships used a condom and 69% used commercial lubricant. Among partnerships that used commercial lubricant, 56% reported lubricant application by both members of the partnership, 66% first applied lubricant during sex, but before penetration, and 98% applied lubricant at multiple locations. The relationship between substance use and commercial lubricant use varied by condom use (interaction p-value = 0.01). Substance use was positively associated with commercial lubricant use within partnerships that did not use condoms during RAI at their last sexual event (adjusted odds ratio [AOR] = 4.47, 95% confidence interval [CI]: 1.63-12.28), but no association was observed within partnerships that did use condoms (AOR = 0.66, 95% CI: 0.23-1.85). Commercial lubricant use during RAI was also positively associated with reporting more sexual partners (AOR = 1.18, 95% CI: 1.05-1.31), while older age (units = 5 years; AOR = 0.75, 95% CI: 0.61-0.94), homelessness (past year; AOR = 0.32, 95% CI: 0.13-0.76), and having sex with an older (>10 years) partner (AOR = 0.37, 95% CI: 0.14-0.95) were negatively associated with commercial lubricant use. These factors should be considered in the development of rectal microbicide gels to enhance their acceptability and use among MSM.
机译：为了指导发展和评估直肠杀菌剂凝胶在男男性接触者（MSM）中预防HIV的潜在用途，我们研究了该人群中接受肛门性交（RAI）期间商业润滑剂使用的动态和背景。从2007年到2010年，居住在洛杉矶的168位接受RAI训练的HIV阴性MSM完成了计算机辅助的自我访谈，在基线，三个月和一年的研究中收集了他们最近与≤3个伴侣发生性行为的信息。访问。使用Logistic广义线性混合模型来确定与参与者在随访过程中报告的421个伙伴关系中在最后一次性事件中在RAI期间使用商业润滑油有关的个人和性事件水平特征。在RAI的最后一次性活动中，有57％的伴侣使用了避孕套，而69％的伴侣使用了商业润滑剂。在使用商业润滑剂的合作伙伴中，有56％的人表示该伙伴双方都使用了润滑剂，其中66％的人在性生活中但未渗透之前首次使用了润滑剂，而98％的人在多个地点使用了润滑剂。物质使用与商业润滑剂使用之间的关系因避孕套使用而异（相互作用p值= 0.01）。在RAI上一次发生性行为时未使用安全套的伙伴关系中，物质的使用与商业润滑剂的使用呈正相关（调整后的优势比[AOR] = 4.47，95％置信区间[CI]：1.63-12.28），但没有关联在使用安全套的伙伴关系中观察到（AOR = 0.66，95％CI：0.23-1.85）。在RAI期间使用商业润滑剂还与报告更多性伴侣（AOR = 1.18，95％CI：1.05-1.31）和年龄较大（单位= 5岁; AOR = 0.75，95％CI：0.61-0.94）呈正相关，无家可归（过去的一年; AOR = 0.32，95％CI：0.13-0.76），并且与年龄较大（> 10岁）的伴侣发生性关系（AOR = 0.37，95％CI：0.14-0.95）与商业润滑剂的使用负相关。在开发直肠杀菌剂凝胶时应考虑这些因素，以增强其在MSM中的可接受性和用途。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号