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首页> 外文期刊>AIDS care. >Differential gender effects of depression on use of HIV medications among HIV-positive Puerto Rican drug users.
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Differential gender effects of depression on use of HIV medications among HIV-positive Puerto Rican drug users.

机译:在艾滋病毒呈阳性的波多黎各吸毒者中,抑郁症对使用艾滋病毒药物的性别影响不同。

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Many barriers to the use of HIV medications have been identified. Research findings have also shown a gender disparity in HIV care behaviors. However, interaction effects of gender with the potential barriers to use of HIV medications among HIV-positive minority drug users remain under-studied. This study examined interaction effects of gender with potential moderating factors (i.e., individual and network characteristics) on the use of HIV medications. Analyses were based on 260 HIV-positive Puerto Rican heroin and cocaine users, recruited in New York (N=178) and Puerto Rico (N=82) in 1998-2003. HIV status was assessed using OraSure, and heroin or cocaine use was verified by urinalysis. All participants were tested and interviewed at baseline and six-month follow-up (183 males; 77 females). In predicting use of HIV medications at follow-up (HIVMEDF), use of HIV medications at baseline (HIVMED), individual characteristics (e.g., depression), network characteristics (e.g., having an intravenous drug user [IDU] sex partner), recruitment site, and interaction effects of these variables with gender, were examined in multiple logistic regression analysis. Use of HIV medications was low (29% at baseline; 40% at follow-up). HIVMED, recruitment site, gender, and depression had significant main effects on HIVMEDF. Depression also had a significant interaction effect with gender on HIVMEDF. Unlike men, women with depression were less likely than women without depression to use the medications. The findings indicate that gender-specific issues should be addressed by treatment programs for HIV-positive drug users, with particular efforts needed to enhance use of medications for depressed women.
机译:已经确定了使用艾滋病毒药物的许多障碍。研究结果还表明,在艾滋病毒护理行为中存在性别差异。但是,在艾滋病毒阳性少数族裔吸毒者中,性别与使用艾滋病毒药物的潜在障碍之间的相互作用影响尚未得到充分研究。这项研究调查了性别与潜在的调节因素(即个体和网络特征)对艾滋病毒药物使用的相互作用。分析基于1998-2003年在纽约(N = 178)和波多黎各(N = 82)招募的260名HIV阳性波多黎各海洛因和可卡因使用者。使用OraSure评估HIV状况,并通过尿液分析验证海洛因或可卡因的使用。在基线和六个月的随访中对所有参与者进行了测试和访谈(男性183例,女性77例)。在预测后续使用HIV药物(HIVMEDF),基线使用HIV药物(HIVMED),个体特征(例如抑郁),网络特征(例如,有静脉吸毒者[IDU]性伴侣),招募中这些位点以及这些变量与性别的相互作用影响,在多重逻辑回归分析中进行了检验。 HIV药物的使用率很低(基线时为29%;随访时为40%)。 HIVMED,招募地点,性别和抑郁对HIVMEDF具有重要的主要影响。抑郁症也与性别对HIVMEDF有显着的相互作用。与男性不同,患有抑郁症的女性比没有抑郁症的女性使用药物的可能性更低。研究结果表明,针对艾滋病毒阳性吸毒者的治疗方案应解决针对性别的问题,尤其需要做出更多努力来增加抑郁症妇女的药物使用。

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