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HIV-related symptoms and patient clusters among Chileans living with HIV

机译：智利艾滋病毒携带者中与艾滋病毒有关的症状和患者群

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Identifying both Human immunodeficiency virus (HIV)-related and co-morbid symptoms experienced by people living with HIV (PLWH) who are receiving antiretroviral therapy (ART) treatment is a major challenge for healthcare providers globally. Yet, little research to date has examined the symptoms of illness experienced by PLWH including patients living in Central and South American. To address this gap, this study was designed to identify symptoms of HIV by socio-demographic and/or clinical characteristics among Chilean patients living with the virus. A convenience sample of 209 Chilean PLWH was recruited from an outpatient clinic in Santiago, Chile. A structured interview was used to elicit socio-demographic information and HIV symptoms status. Additional clinical information was obtained through a review of the participants' medical records. Results show that patients most commonly reported HIV-related symptoms were fear/worries (66%), anxiety (52%), gas/bloating (50%), and thirst (50%). Multivariate analysis revealed a positive association between the number of reported HIV-related symptoms and number of years living with HIV. Having completed college was negatively associated with number of symptoms. Latent class analysis indicated that PLWH in the sample who had completed college were two times more likely to experience a mild intensity of HIV-related symptoms than their lesser educated counterparts. Similarly, logistic regression revealed that college-educated PLWH were twice as likely to be classified in the subgroup reporting mild intensity of symptoms than those who lacked a college degree. Overall, the study's results reveal that many Chilean PLWH, even those with high CD4 counts and low or undetectable viral loads, are not symptom free. The findings point to the need for clinicians to tailor a plan of care for individuals living with HIV that is based on their symptomatology. ? 2013
机译：识别正在接受抗逆转录病毒疗法（ART）治疗的HIV感染者（PLWH）所经历的与人类免疫缺陷病毒（HIV）相关的症状和并存症状是全球医疗服务提供商面临的主要挑战。然而，迄今为止，很少有研究检查PLWH所经历的疾病症状，包括生活在中美洲和南美的患者。为了弥补这一差距，本研究旨在通过社会人口统计学和/或临床特征在患有该病毒的智利患者中鉴定HIV症状。从智利圣地亚哥的一家门诊诊所招募了209名智利PLWH的便利样本。使用结构化访谈来获取社会人口统计学信息和HIV症状状态。通过查看参与者的病历，可以获得更多的临床信息。结果表明，最常报告的与HIV相关的症状是恐惧/担忧（66％），焦虑（52％），气体/腹胀（50％）和口渴（50％）。多变量分析显示，报告的与艾滋病相关的症状数量与感染艾滋病毒的年限之间呈正相关。大学毕业与症状数量呈负相关。潜在类别分析表明，完成大学学业的样本中，艾滋病毒/艾滋病感染者轻度感染艾滋病毒相关症状的可能性是受教育程度较低的人群的两倍。同样，逻辑回归分析显示，受过大学教育的PLWH被归类为症状较轻的亚组的可能性是缺乏大学学历的PLWH的两倍。总体而言，研究结果表明，许多智利的PLWH，即使CD4计数高，病毒载量低或无法检测到的人，也并非没有症状。研究结果表明，临床医生有必要根据其症状对艾滋病毒感染者制定护理计划。 ？ 2013年

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