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首页> 外文期刊>AIDS care. >Gender differences in antiretroviral treatment outcomes of HIV patients in rural Uganda.
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Gender differences in antiretroviral treatment outcomes of HIV patients in rural Uganda.

机译：乌干达农村地区艾滋病毒患者抗逆转录病毒治疗结果的性别差异。

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摘要

Gender differences in treatment outcomes of 305 persons living with HIV receiving antiretroviral treatment (ART) in Kabarole district, western Uganda, were evaluated. The primary treatment outcome was virological suppression defined as HIV-1 RNA viral load (VL) <400 copies/ml and the secondary outcome measure was the increase in the CD4 cell count after six months on ART. Statistical analysis included descriptive, univariate, and multivariate methods. Proportionally, more females chose to seek treatment compared to males. After six months of treatment, females were more likely to have viral suppression (VL > 400 copies/ml) as compared to males (odds ratio 2.14, 95% confidence interval 0.99-4.63, p=0.05). While females had a significantly higher baseline CD4 cell count at initiation of treatment compared to males, the increase in CD4 cell count after six months on ART was similar in males and females. The reasons for better ART outcomes for females should be further investigated. Ideally, ART programs should work toward equitable treatment outcomes for men and women, if the cause of the gender differential lies in patient behavior and the way ART services are delivered.
机译：评估了乌干达西部卡巴罗莱区接受抗逆转录病毒治疗（ART）的305名艾滋病毒感染者的治疗结果中的性别差异。主要治疗结果是病毒学抑制，定义为HIV-1 RNA病毒载量（VL）<400拷贝/ ml，次要结果是在接受ART治疗六个月后CD4细胞计数增加。统计分析包括描述性，单变量和多变量方法。按比例，与男性相比，选择寻求治疗的女性更多。治疗六个月后，女性比男性更容易受到病毒抑制（VL> 400拷贝/毫升）（优势比2.14，95％置信区间0.99-4.63，p = 0.05）。尽管女性在治疗开始时的基线CD4细胞计数明显高于男性，但在ART治疗六个月后，男性和女性的CD4细胞计数增加相似。女性抗逆转录病毒治疗效果更好的原因应进一步研究。理想情况下，如果性别差异的原因在于患者的行为和ART服务的提供方式，则ART计划应努力实现男女平等的治疗结果。

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