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首页> 外文期刊>AIDS care. >Using motivational interviewing to promote adherence to antiretroviral medications: a randomized controlled study.
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Using motivational interviewing to promote adherence to antiretroviral medications: a randomized controlled study.

机译：使用动机访谈来促进对抗逆转录病毒药物的依从性：一项随机对照研究。

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The primary aim of this study was to test an intervention to support antiretroviral medication adherence among primarily low-income men and women with HIV. The study was a randomized controlled trial (Get Busy Living) with participants assigned to treatment (Motivational Interviewing [MI]) and control groups. Participants were recruited from an HIV/AIDS clinic in Atlanta, Georgia, US. Of those referred to the study, 247 completed a baseline assessment and were enrolled with 125 randomized to the intervention group and 122 to the control group. Participants were patients beginning antiretroviral therapy or changing to a new drug regimen. The intervention consisted of five MI sessions delivered by registered nurses in individual counselling sessions. Participants were paid for each session attended. The intervention sought to build confidence, reduce ambivalence and increase motivation for ART medication-taking. Medication adherence was measured by the Medication Event Monitoring System (MEMS) from the time of screening until the final follow-up conducted approximately 12 months following the baseline assessment. Participants in the intervention condition showed a trend towards having a higher mean percent of prescribed doses taken and a greater percent of doses taken on schedule when compared to the control group during the months following the intervention period. This effect was noted beginning at about the eighth month of the study period and was maintained until the final study month. Although the finding was weaker for overall percent of prescribed doses taken, the results for the percent of doses taken on schedule suggests that the MI intervention may be a useful approach for addressing specific aspects of medication adherence, such as adherrence to a specified dosing schedule.
机译：这项研究的主要目的是测试一种干预措施，以支持主要针对低收入男性和女性艾滋病毒感染者的抗逆转录病毒药物依从性。这项研究是一项随机对照试验（忙碌生活），参与者被分配到治疗组（动机访谈[MI]）和对照组。参与者是从美国佐治亚州亚特兰大市的一家艾滋病毒/艾滋病诊所招募的。在涉及该研究的那些研究中，有247位完成了基线评估，并随机入选了125位干预组和122位对照组。参加者是开始抗逆转录病毒治疗或改用新药治疗的患者。干预包括注册护士在个人辅导会议中进行的五次心律失常会议。每次参加会议均向参与者付费。该干预旨在建立信心，减少矛盾情绪并增加服用抗逆转录病毒药物的动机。从筛查到基线评估后约12个月进行最终随访，药物事件监测系统（MEMS）对药物依从性进行了测量。干预期后的几个月中，与对照组相比，干预条件下的参与者呈现出趋向于具有更高的平均处方剂量百分比和更大的进度百分比剂量的趋势。从研究期的第8个月开始注意到这种效果，并一直持续到最后一个研究月。尽管对于规定剂量的总体百分比发现不强，但按计划剂量百分比的结果表明，MI干预可能是解决药物依从性特定方面（例如遵守指定给药方案）的有用方法。

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