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首页> 外文期刊>The American Journal of Cardiology >Impact of Right Ventricular Pacing in Patients Who Underwent Implantation of Permanent Pacemaker After Transcatheter Aortic Valve Implantation
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Impact of Right Ventricular Pacing in Patients Who Underwent Implantation of Permanent Pacemaker After Transcatheter Aortic Valve Implantation

机译：经经管主动脉瓣植入经减缓术后永久性起搏器患者右心室起搏的影响

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摘要

Atrioventricular conduction disturbances requiring implantation of permanent pacemaker (PPM) are a common complication following transcatheter aortic valve implantation (TAVI). Previous registry data are conflicting but suggestive of an increased risk in heart failure admissions in the post-TAVI PPM cohort. Given the expanding use of TAVI, the present study evaluates the effects of chronic right ventricular pacing (RV pacing) in post-TAVI patients. This is a single-center study of 672 patients who underwent TAVI from 2011 to 2017 of which 146 underwent PPM. Follow-up 1-year post-TAVI outcome data were available for 55 patients and were analyzed retrospectively. Patients who underwent PPM were more likely to have heart failure admissions (17.1% vs 10.1%; hazard ratio [HR] 1.70; 95% confidence interval [CI] 1.10 to 2.64; p 0.019) and a trend toward increased mortality (21.9% vs 15.4%; HR 1.42; 95% CI 0.99 to 2.05; p 0.062). At 1-year follow-up, 30 of 55 (54.5%) patients demonstrated >40% RV pacing. Compared with patients who had 40% RV pacing were more likely to have heart failure admissions (8% vs 40%; HR 5.0; 95% CI 1.23 to 20.27; p 0.007) and demonstrated a trend toward increased mortality (12% vs 33.3%; HR 2.78; 95% CI 0.86 to 9.00; p 0.064). This is suggestive that the post-TAVI PPM cohort is particularly sensitive to chronic RV pacing.
机译：需要植入永久性起搏器（PPM）的房室传导障碍是经截面主动脉瓣植入（Tavi）后的常见并发症。以前的注册表数据是矛盾的，但暗示Tavi PPM队列中的心力衰竭录取风险增加。鉴于Tavi的扩张使用，本研究评估了Tavi患者慢性右心室起搏（RV起搏）的影响。这是对2011年至2017年TAVI接受TAVI的672名患者的单一中心研究，其中146次接受了PPM。 55名患者可获得随访1年的TAVI后TAVI结果数据，并回顾性分析。接受PPM的患者更有可能具有心力衰竭录取（17.1％vs10.1％;危害比[HR] 1.70; 95％置信区间[CI] 1.10至2.64; p 0.019）和增加死亡率的趋势（21.9％vs 15.4％; HR 1.42; 95％CI 0.99至2.05; p 0.062）。在1年的随访中，55个（54.5％）患者的30％（54.5％）显示> 40％RV起搏。与40％RV起搏的患者相比，患有心力衰竭的录取（8％与40％; HR 5.0; 95％CI 1.23至20.27; p 0.27）并表现出增加死亡率的趋势（12％与33.3％增加） ; HR 2.78; 95％CI 0.86至9.00; p 0.064）。这表明Tavi PPM队列对慢性RV起搏特别敏感。

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  • 来源
    《The American Journal of Cardiology》 |2018年第10期|共6页
  • 作者

    Fahd Nadeem; Takahiro Tsushima; Thomas P. Ladas; Rahul B. Thomas; Sandeep M. Patel; Petar Saric; Toral Patel; Jerry Lipinski; Jun Li; Marco A. Costa; Daniel I. Simon; Ankur Kalra; Guillherme F. Attizzani; Mauricio S. Arruda; Judith Mackall; Sergio G. Thal;

  • 作者单位

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Case Western Reserve University;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

    Harrington Heart and Vascular Institute University Hospitals Cleveland Medical Center;

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  • 正文语种 eng
  • 中图分类 心脏、血管（循环系）疾病;
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