Findings of a relation between vitamin D and C-reactive protein: Concerns about methods used and conclusions drawn

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Findings of a relation between vitamin D and C-reactive protein: Concerns about methods used and conclusions drawn

机译：维生素D和C反应蛋白质之间的结果：对使用方法的担忧和得出的结论

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The epidemiologic study suggesting a relation between serum 25-hydroxy vitamin D (25[OH]D) and C-reactive protein (CRP) by Amer and Qayyum is timely, given the prominence of 25(OH)D in recent scientific research and the recent increase in vitamin D recommended daily allowances.2 However, the study appears to suffer from deficiencies in internal validity (due to the analysis methods used) and external validity (because vitamin D supplementation by subjects was not included in the analysis). Their findings contradict evidence for a dose-dependent reduction of coronary heart disease mortality with higher serum 25(OH)D, and furthermore, CRP has questionable utility in guiding treatment of patients with coronary heart disease. Best practices in data analysis suggest several steps that should have been taken to avoid bias and uncertainty.

机译：表明血清25-羟基维生素D（25 [OH] D）和C-反应蛋白（CRP）与Amer和C-反应蛋白（CRP）之间的关系及时，据近期科学研究和Qualifice的突出最近的维生素D增加了每日津贴的推荐。他们的研究结果与冠心病死亡率的剂量依赖性降低了冠心病死亡率，并且此外，CRP在引导冠心病患者的治疗方面具有可疑的效用。数据分析中的最佳实践表明应该采取几个步骤来避免偏见和不确定性。

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《The American Journal of Cardiology》 |2012年第1期|共2页
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正文语种 eng
中图分类心脏、血管（循环系）疾病;
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1. Findings of a relation between vitamin D and C-reactive protein: Concerns about methods used and conclusions drawn [J] . The American Journal of Cardiology . 2012,第1期

机译：维生素D和C反应蛋白质之间的结果：对使用方法的担忧和得出的结论
2. Relation of Genetic Variation in the Gene Coding for C-Reactive Protein with Its Plasma Protein Concentrations: Findings from the Women's Health Initiative Observational Cohort [J] . Cathy C Lee Nai-chieh Yuko You Yiqing Song Yi-Hsiang Hsu JoAnn Manson Lauren Nathan Lesley Tinker Simin Liu Clinical Chemistry . 2009,第2期

机译：C反应蛋白基因编码中的遗传变异与其血浆蛋白浓度的关系：来自妇女健康倡议观察队列的发现
3. Relation of Genetic Variation in the Gene Coding for C-Reactive Protein with Its Plasma Protein Concentrations: Findings from the Women’s Health Initiative Observational Cohort [J] . Cathy C. Lee, JoAnn Manson, Lauren Nathan, Clinical Chemistry: Journal of the American Association for Clinical Chemists . 2009,第2期

机译：C反应蛋白基因编码中的遗传变异与血浆蛋白浓度的关系：妇女健康倡议观察队列的发现
4. Relation of heart rate variability to serum levels of C-reactive protein in patients with severe sepsis and septic shock [C] . Papaioannou V.P., Dragoumanis C.D., Pneumatikos I.P. Computers in Cardiology, 2009 . 2009

机译：严重败血症和败血性休克患者心率变异性与血清C反应蛋白水平的关系
5. Effect of vitamin D supplementation on C-reactive protein and insulin resistance in postmenopausal women with type 2 diabetes mellitus. [D] . Flores, Mario E. 2010

机译：补充维生素D对2型糖尿病绝经后妇女C反应蛋白和胰岛素抵抗的影响。
6. Relation of Genetic Variation in the Gene Coding for C-Reactive Protein with its Plasma Protein Concentrations: Findings from the Women’s Health Initiative Observational Cohort [O] . Cathy C. Lee, Nai-chieh Yuko You, Yiqing Song, -1

机译：C反应蛋白基因编码中的遗传变异与血浆蛋白浓度的关系：妇女健康倡议观察队列的发现
7. An Expression of Concern from The Journal of Nutrition's Editorial Office about: Vitamin D Supplementation Affects Serum High-Sensitivity C-Reactive Protein, Insulin Resistance, and Biomarkers of Oxidative Stress in Pregnant Women [O] . Zatollah Asemi, Mansooreh Samimi, Zohreh Tabassi, 2020

机译：营养编辑部杂志的关注：维生素D补充对孕妇氧化胁迫的血清高敏感性C反应蛋白，胰岛素抵抗力和生物标志物影响

Findings of a relation between vitamin D and C-reactive protein: Concerns about methods used and conclusions drawn

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