Usefulness and Safety of Rivaroxaban in Patients Following Isolated Mitral Valve Replacement With a Mechanical Prosthesis

André R. Dur?es; Yasmin de S.L. Bitar; Maria Luiza G. Lima; Caroline C. Santos; Igor S. Schonhofen; José Admir?o L. Filho; Leonardo Roever

首页> 外文期刊>The American Journal of Cardiology >Usefulness and Safety of Rivaroxaban in Patients Following Isolated Mitral Valve Replacement With a Mechanical Prosthesis

【24h】

Usefulness and Safety of Rivaroxaban in Patients Following Isolated Mitral Valve Replacement With a Mechanical Prosthesis

机译：用机械假体置换孤立二尖瓣置换后患者的蓖麻油的用途和安全性

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Rivaroxaban has previously been tested in experimental and animal models with encouraging results. We prospectively selected seven patients between May 2017 and January 2018 who underwent isolated mitral valve replacement with a mechanical prosthesis and had unstable INR control at least 3 months after surgery. An intervention of rivaroxaban 15mg was then administered twice daily for a period of 90days. No patient presented intracardiac thrombus, reversible ischemic neurological deficit, ischemic or hemorrhagic stroke, and hospitalization or death during 3 months of follow-up. Two patients eradicated the presence of spontaneous echo contrast. Mean and peak pressure gradients, peak velocity, effective orifice area, and PHT were similar before and after the intervention. In conclusion, the use of rivaroxaban for 90days in seven patients after replacement of mitral valve with the mechanical prosthesis did not present thromboembolic or bleeding events (NCT02894307).

机译：Rivaroxaban先前已经在实验和动物模型中进行了测试，令人鼓舞的结果。我们在2017年5月和2018年5月期间展示了七名患者，他在手术后至少3个月内遭受了孤立的二尖瓣替代，并且在手术后至少3个月内患有不稳定的INR。然后每天施用蓖麻油45mg的干预，每天持续90天。没有患者在3个月随访期间呈现内心血管血栓，可逆缺血性神经缺陷，缺血性或出血性卒中，以及住院或死亡。两名患者消除了自发回声对比的存在。平均和峰值压力梯度，峰值速度，有效孔口和PHT在干预之前和之后类似。总之，在用机械假体更换二尖瓣后，在7名患者中使用Rivaroxaban的使用不存在血栓栓塞或出血事件（NCT02894307）。

著录项

来源
《The American Journal of Cardiology》 |2018年第6期|共4页
作者
André R. Dur?es; Yasmin de S.L. Bitar; Maria Luiza G. Lima; Caroline C. Santos; Igor S. Schonhofen; José Admir?o L. Filho; Leonardo Roever;
展开▼
作者单位

General Hospital Roberto Santos;

General Hospital Roberto Santos;

General Hospital Roberto Santos;

General Hospital Roberto Santos;

General Hospital Roberto Santos;

General Hospital Roberto Santos;

Leonardo Roever: Uberlandia Federal University;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类心脏、血管（循环系）疾病;
关键词

相似文献

外文文献
中文文献
专利

1. Usefulness and Safety of Rivaroxaban in Patients Following Isolated Mitral Valve Replacement With a Mechanical Prosthesis [J] . André R. Dur?es, Yasmin de S.L. Bitar, Maria Luiza G. Lima, The American Journal of Cardiology . 2018,第6期

机译：用机械假体置换孤立二尖瓣置换后患者的蓖麻油的用途和安全性
2. Impact of prosthesis-patient mismatch on the regression of secondary mitral regurgitation after isolated aortic valve replacement with a bioprosthetic valve in patients with severe aortic stenosis [J] . AngeloniE., MelinaG., PibarotP., Circulation. Cardiovascular imaging . 2012,第1期

机译：严重的主动脉瓣狭窄患者中，假体-患者失配对继发性二尖瓣反流消退的影响
3. Star GK Bileaflet Mechanical Valve Prosthesis-Patient Mismatch after Mitral Valve Replacement: A Chinese Multicenter Clinical Study [J] . Hua Cao, Zhihuang Qiu, Liangwan Chen, Medical science monitor : . 2015,第1期

机译：Star GK Bileaflet二尖瓣置换术后机械瓣膜假体-患者不匹配：一项中国多中心临床研究
4. Analysis of spectral features of mechanical heart valve sounds after aortic and mitral valve replacement [C] . Altunkaya Sabri, Kara Sadik, Gormus Niyazi, 2010 15th National Biomedical Engineering Meeting . 2010

机译：主动脉和二尖瓣置换术后机械性心脏瓣膜声音的频谱特征分析
5. Transcatheter Mitral Valve Replacement: Structural and Hemodynamic Analysis [D] . ?Ravaghi, Saba 2020

机译：经导管二尖瓣置换：结构和血流动力学分析
6. Star GK Bileaflet Mechanical Valve Prosthesis-Patient Mismatch After Mitral Valve Replacement: A Chinese Multicenter Clinical Study [O] . Hua Cao, Zhihuang Qiu, Liangwan Chen, 2015

机译：二尖瓣置换术后Star GK Bileaflet机械瓣膜假体-患者不匹配：一项中国多中心临床研究
7. P1246Age-, body size-, and sex-specific reference values for tricuspid valve apparatus parameters by real-time three-dimensional transthoracic echocardiographyP1247Surgical therapy in infective endocarditis: predisposing and prognostic factorsP1248Evalutation of MV annulus geometry modifications before and after mitraclip implantation with 3D transesophageal echocardiographyP1249Prognostic echocardiographic parameters for successful transcatheter edge-to-edge mitral valve repairP1250Influence of body surface area in diagnosis and outcome patient-prosthesis mismatch after TAVI. Is it necessary to adjust for ideal body weight?P1251Outcome of paradoxical low-flow low-gradient severe AS following TAVI: paradoxical VS parallel to outcome of high gradient ASP1252Prognostic role of cardiac calcifications in subjects without overt significant heart disease and previous cardiovascular events: is there an additive value over cardiovascular risk factors scores?P1253Aging degeneration of mitral valve without leaflet prolapse or tethering as a cause of severe mitral regurgitationP1254Cardiovascular risk assessment should be performed in patients with incidental aortic sclerosisP1255Cardiac valve calcification score: simple 2D echocardiographic tool for cardiovascular risk stratification in patients with chronic renal failureP1256Diastolic mitral regurgitation following transcatheter aortic valve replacement: prevalence, predictors and impact on outcomesP1257Timing of myocardial shortening determines left ventricular regional remodelling in hearts with conduction delaysP1258Myocardial stiffness assessment using shear wave imaging in healthy children and hypertrophic cardiomyopathyP1259Assessment of right ventricular response to exercise using vector velocity imaging in hypertrophic cardiomyopathyP1260Diagnostic value of cardiac biomarkers (high sensitive troponin T and N-terminal pro-brain natriuretic peptide) in patients with infiltrative cardiomyopathiesP1261Right ventricular global longitudinal strain differentiates between adolescent patients with definite, borderline and possible ARVC and controlsP1262 echogrqphic predictif factors of atrial arrhythmias in patients with arrhythmogenic right ventricular dysplasiaP1263Importance of combined left atrial size and estimated pulmonary pressure for clinical outcome in patients presenting with heart failure with preserved ejection fractionP1264Chronotropic response in mitochondrial (ANT1) cardiomyopathyP1265 The effect of cardiovascular risk factors and cancer type in anthracycline's cardiotoxicityP1266Revisiting the echocardiographic features of acute myocarditisP1267Altered circulation in fetuses of diabetic mothers: a fetal computational model analysisP1268Increased epicardial adipose tissue is related to stress-induced cardiomyopathyP1269Contrast enhanced ultrasound of kidney perfusion in patients with renal artery stenosis: diagnostic and prognostic applications. [O] . F. Ancona, R. Ilhao Moreira, V. Lavanco, 2016

机译：P1246age-，身体大小和性别特异性参考Tricuspid阀装置参数通过实时三维经线性超声心动图124772777777747774747478EVALIGUTALMEXP1249预期植入前后MV环形植入前后MV环空性修饰。超声心动图参数用于成功的经截管边缘到边缘二尖瓣修复P1250中的体表面积诊断和结果患者假体在Tavi后的不匹配。是否有必要调整理想的体重？P1251矛盾的低流量低梯度严重，如Tavi：矛盾的VS平行于高梯度ASP1252的结果，在没有明显显着的心脏病和以前心血管事件的情况下心脏钙化的促傲作用患有心血管危险因素的添加剂值分数？没有传单脱垂的二尖瓣退化或作为严重二尖瓣血管血管血管病风险评估的患者进行脱垂或系绳，应当在偶然主动脉源肺源P1255Cariac阀钙化评分患者中进行：用于心血管风险分层的简单2D超声心动图工具在慢性肾功能衰竭的患者中，经沟管主动脉瓣膜置换术后：流行率，预测因子和对Otcomasp1257的影响，心肌缩短决定了导通延迟的心中的剩余心室区域重新耦合258MYCIARIAL僵硬评估使用剪切波成像在健康儿童和肥厚性心肌脑病中的舒缓性心脏响应，在渗透心肌肌瘤患者中使用载体速度成像的培养速度成像（高敏感的肌钙蛋白T和N-末端脑Natrietic肽）渗透心肌病，患者心室全局纵向菌株在患有心律失常右心室发育不良患者的心理心律失常患者中的青少年患者与Controlsp1262 echogrqphic预测因子的分歧，患者心血性右心室发育不良患者患者患者患者患者患者患者患者患者患者线粒体（ANT1）心肌病患者的喷射FRACTIONP1264系列响应1265心血管危险因素和癌症类型在蒽丙烯的心肌毒性皮1126660中的影响访问患有糖尿病母亲胎儿胎儿急性心肌炎的超声心动图，患者患者：胎儿计算模型分析P1268增加外膜脂肪组织与肾动脉狭窄患者肾脏灌注的应激诱导的心肌病，增强超声波：诊断和预后应用。

Usefulness and Safety of Rivaroxaban in Patients Following Isolated Mitral Valve Replacement With a Mechanical Prosthesis

摘要

著录项

相似文献

相关主题

期刊订阅