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Impact of a nutritional counseling program on prevention of HAART-related metabolic and morphologic abnormalities.

机译:营养咨询计划对预防HAART相关代谢和形态异常的影响。

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The advent of highly active antiretroviral therapy (HAART) improved HIV infection prognosis. However, adverse metabolic and morphologic effects emerged, highlighting a lack of investigation into the role of nutritional interventions among this population. The present study evaluated the impact of a nutritional counseling program on prevention of morphologic and metabolic changes in patients living with HIV/AIDS receiving HAART. A 12-month randomized clinical trial was conducted with 53 adults of both genders in use of HAART. Subjects were allocated to either an intervention group (IG) or a control group (CG). Nutritional counseling was based on the promotion of a healthy diet pattern. Anthropometrical, biochemical, blood pressure, and food intake variables were assessed on four separate occasions. Sub scapular skin-fold results showed a significant tendency for increase between time 1 (Mean IG = 14.9 mm; CG = 13.6 mm), time 3 (Mean IG = 16.7 mm; CG = 18.2 mm), and time 4 (Mean IG = 16.4 mm; CG = 17.7 mm). Lipid percentage intake presented a greater increase among controls (time 1 mean = 26.3%, time 4 mean = 29.6%) than among IG subjects (time 1 mean = 29.1%, time 4 mean = 28.9%). Moreover, participants allocated to the IG presented an increase in dietetic fiber intake of almost 10 grams. The proposed nutritional counseling program proved to be effective in improving diet by reducing fat consumption and increasing fiber intake.
机译:高效抗逆转录病毒疗法(HAART)的出现改善了HIV感染的预后。但是,出现了不利的代谢和形态学影响,这突出表明缺乏对该人群营养干预作用的调查。本研究评估了营养咨询计划对预防接受HAART的HIV / AIDS病人形态和代谢变化的预防作用。一项为期12个月的随机临床试验针对53名男女使用HAART进行。将受试者分配到干预组(IG)或对照组(CG)。营养咨询是基于促进健康饮食方式的。在四个不同的场合评估了人体测量学,生化,血压和食物摄入量变量。肩cap下皮褶皱结果显示在时间1(平均IG = 14.9 mm; CG = 13.6 mm),时间3(平均IG = 16.7 mm; CG = 18.2 mm)和时间4(平均IG = 16.4毫米; CG = 17.7毫米)。对照中的脂类摄入量(时间1平均值= 26.3%,时间4平均值= 29.6%)比IG受试者(时间1平均值= 29.1%,时间4平均值= 28.9%)有更大的增加。此外,分配给IG的参与者膳食纤维摄入量增加了近10克。拟议的营养咨询计划通过减少脂肪消耗和增加纤维摄入量,有效改善了饮食。

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