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User experiences and acceptability attributes of the diaphragm and lubricant gel in an HIV prevention trial in southern Africa.

机译:在南部非洲的一项HIV预防试验中,隔膜和润滑剂凝胶的用户体验和可接受性属性。

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摘要

Methods for Improving Reproductive Health in Africa (MIRA), a phase III HIV prevention trial, was conducted among 5039 Zimbabwean and South African women to test the Ortho All-Flex diaphragm and Replens((R)) lubricant gel. Among the 2418 intervention group participants, 105 women who had completed the trial and 41 male partners participated in focus group discussions and in-depth interviews about the acceptability of the diaphragm and gel and their experiences using the study products. Women who participated in the qualitative study had exited the trial in the prior nine months, were HIV negative, and used the diaphragm and gel for 12-24 months. The comprehensive and flexible conceptual framework was applied to investigate the salient attributes for acceptability of the products as potential HIV prevention methods, and emerging themes for acceptability were framed within three categories of attributes (product, relationship, and sexual intercourse attributes). Both diaphragm and gel were found to be highly acceptable in the study group, and the gel was popular due to its effect of enhancing sexual pleasure. Some of the important product attributes influencing acceptability as reported by users were convenience, ease of use, dual use potential for contraception and disease prevention, and being female-initiated. It was also noted that some elements (such as sexual pleasure, couple communication, and the necessity of diaphragm negotiation) could be more important than others in terms of influencing product acceptability and use. Acceptability attributes reflective of the broader contextual environment (beliefs generated in the trial community suggesting preventive efficacy - preventive method optimism - and gendered norms favoring male superiority in sexual decision making) also emerged as important themes. The high level of acceptability of the diaphragm and gel among MIRA trial participants and their male partners is an indicator of the continued need for an effective female-initiated product.
机译:在5039名津巴布韦人和南非妇女中进行了III期HIV预防试验,旨在改善非洲生殖健康的方法(MIRA),以测试Ortho All-Flex隔膜和Replens(R)润滑剂凝胶。在2418名干预小组参与者中,有105名完成试验的妇女和41名男性伙伴参加了有关隔膜和凝胶的可接受性及其使用研究产品的经验的焦点小组讨论和深入访谈。参加定性研究的女性在之前的9个月中退出了试验,HIV阴性,并且使用隔膜和凝胶剂治疗了12-24个月。应用了全面而灵活的概念框架来调查产品可接受性的显着属性,作为潜在的HIV预防方法,新出现的可接受性主题则分为三类属性(产品,关系和性交属性)。在研究组中发现隔膜和凝胶均高度可接受,并且由于其增强性快感的作用,凝胶很受欢迎。用户报告的一些影响可接受性的重要产品属性包括便利性,易用性,避孕和疾病预防的双重使用潜力以及女性发起的行为。还应注意,就影响产品的可接受性和使用而言,某些因素(例如性快感,夫妻交流和进行隔膜谈判的必要性)可能比其他因素更为重要。可以接受的属性也反映了更广泛的背景环境(在试验社区中产生的信念表明,预防效果-预防方法的乐观态度-以及在男性或女性的性决策中偏重男性优势的性别规范)也已成为重要主题。 MIRA试验参与者及其男性伴侣对隔膜和凝胶的接受度很高,这表明仍需要有效的女性引发产品。

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