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Treatment as prevention: Are Argentinean HIV care providers willing to adopt earlier antiretroviral therapy?

机译:作为预防的治疗:阿根廷的HIV护理提供者是否愿意采用较早的抗逆转录病毒疗法?

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摘要

HIV guidelines increasingly recommend antiretroviral therapy (ART) initiation at a higher CD4 levels. The extent to which these evolving standards are translated into routine clinical care has not been evaluated in Argentina. During October 2012, we conducted an online survey among Argentinean HIV clinicians to assess their attitudes and practices toward ART initiation and its potential use for HIV prevention. Of the 280 physicians included, 61% would prescribe ART at CD4 ≤500 cells/L for asymptomatic patients. Although, only 11% would recommend ART irrespective of CD4 cell count, 72% would do it for serodiscordant couples, and 75% for sex workers. Most participants agreed that they would consider earlier initiation of ART if transmission risk exists, and that expansion of ART could help decrease HIV incidence. These results suggest that a large proportion of Argentinean HIV care providers are willing to adopt the recently updated Argentinean guidelines recommending earlier ART, especially when high HIV transmission risk exists.
机译:HIV指南越来越多地建议以较高的CD4水平开始抗逆转录病毒疗法(ART)。在阿根廷尚未评估这些不断发展的标准转换为常规临床护理的程度。 2012年10月,我们在阿根廷的HIV临床医生中进行了一项在线调查,以评估他们对抗病毒治疗的态度和做法以及抗病毒治疗的潜在用途。在包括的280位医生中,有61%会为无症状患者开出CD4≤500细胞/ L的抗病毒药。尽管与CD4细胞计数无关,只有11%的人会推荐抗逆转录病毒疗法,但对浆膜溶血性伴侣来说,这一比例为72%,对于性工作者则为75%。大多数参与者同意,如果存在传播风险,他们将考虑尽早开始抗病毒治疗,并且扩大抗病毒治疗可以帮助降低艾滋病毒的发病率。这些结果表明,很大一部分阿根廷HIV护理提供者愿意采用最近更新的阿根廷指南,推荐更早的抗病毒治疗,尤其是在存在高HIV传播风险的情况下。

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