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首页> 外文期刊>The Journal of extra-corporeal technology >Application of Micropore Filter Technology: Exploring the Blood Flow Path in Arterial-Line Filters and Its Effect on Bubble Trapping Functions
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Application of Micropore Filter Technology: Exploring the Blood Flow Path in Arterial-Line Filters and Its Effect on Bubble Trapping Functions

机译：微孔过滤技术的应用：探索动脉线过滤器中的血流路径及其对泡沫诱捕功能的影响

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Conventional arterial-line filters commonly use a large volume circular shaped housing, a wetted micropore screen, and a purge port to trap, separate, and remove gas bubbles from extracorporeal blood flow. Focusing on the bubble trapping function, this work attempts to explore how the filter housing shape and its resulting blood flow path affect the clinical application of arterial-line filters in terms of gross air handling. A video camera was used in a wet-lab setting to record observations made during gross air-bolus injections in three different radially designed filters using a 30-70% glycerol-saline mixture flowing at 4.5 L/min. Two of the filters both had inlet ports attached near the filter-housing top with bottom oriented outlet ports at the bottom, whereas the third filter had its inlet and outlet ports both located at the bottom of the filter housing. The two filters with top-in bottom-out fluid paths were shown to direct the incoming flow downward as it passed through the filter, placing the forces of buoyancy and viscous drag in opposition to each other. This contrasted with the third filter's bottom-in bottom-out fluid path, which was shown to direct the incoming flow upward so that the forces of buoyancy and viscous drag work together. The direction of the blood flow path through a filter may be important to the application of arterial-line filter technology as it helps determine how the forces of buoyancy and flow are aligned with one another.
机译：传统的动脉线过滤器通常使用大容量圆形壳体，湿润的微孔筛和吹扫端口，以捕获，分开和去除来自体外血流的气泡。专注于泡沫诱捕​​功能，这项工作试图探讨过滤器外壳形状及其所产生的血流路径如何影响动脉线过滤器在总空气处理方面的临床应用。在湿式实验室设置中使用了一种摄像机，以记录在三种不同径向设计过滤器中的毛刮板注射过程中的观察，使用30-70％的甘油 - 盐水混合物流动在4.5升/分钟。两个过滤器都有入口端口，底部有底部取向的出口端口附近，而第三滤波器的入口和出口位于过滤器壳体的底部。具有顶部底部底部流体路径的两个过滤器被示出，在通过过滤器时向下引导进入流动，将浮力和粘性阻力放置在彼此相对的情况下。这与第三滤波器的底部底部流体路径形成对比，这被示出了将进入的流向向上引导，使得浮力和粘性拖动的力一起工作。通过过滤器的血流路径的方向对动脉线过滤技术的应用可能是重要的，因为它有助于确定浮力和流动的力彼此对齐的方式。

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