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Acceptability and feasibility of serial HIV antibody testing during pregnancy/postpartum and male partner testing in Tororo, Uganda

机译:乌干达托罗罗在怀孕/产后进行系列HIV抗体检测以及男性伴侣检测的可接受性和可行性

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Our objective was to determine whether serial HIV testing during pregnancy and the postpartum period as well as male partner testing are acceptable and feasible in Tororo, Uganda. This was a prospective study of pregnant women at the Tororo District Hospital (TDH) Antenatal Clinic. Patients presenting for routine antenatal care were asked to participate in a serial HIV testing integrated into standard antenatal and postpartum/child immunization visits, and to invite their male partners for HIV testing. Serial testing was defined as ≥2 tests during pregnancy and ≥2 tests within 24 weeks postpartum. Of the 214 enrolled women, 80 (37%) completed serial testing, 176 (82%) had ≥2 tests, and 147 (69%) had ≥3 tests during the study period. One hundred eighty-two women (85%) accepted male partner testing, but only 19 men (10%) participated. One woman seroconverted during the study, for a cumulative HIV incidence of 0.5% (1/214). In multivariable logistic regression analysis, longer distance between home and clinic (aOR 0.87 [95% CI 0.79-0.97]) and not knowing household income (aOR 0.30 [95% CI 0.11-0.84]) were predictive of not completing serial testing. Higher level of education was associated with completing serial testing (linear trend p value = 0.05). In conclusion, partial serial HIV testing was highly acceptable and feasible, but completion of serial testing and male partner testing had poor uptake.
机译:我们的目的是确定在乌干达托罗罗,怀孕和产后的一系列艾滋病毒检测以及男性伴侣检测是否可接受和可行。这是托罗罗地区医院(TDH)产前诊所对孕妇进行的前瞻性研究。要求接受常规产前检查的患者参加一系列艾滋病毒检测,这些检测已整合到标准的产前和产后/儿童免疫检查中,并邀请其男性伴侣进行艾滋病毒检测。串行测试定义为怀孕期间≥2次测试,以及产后24周内≥2次测试。在研究期间,纳入的214位女性中,有80位(37%)完成了连续测试,其中176位(82%)进行了≥2次测试,而147位(69%)进行了≥3次测试。一百八十二名女性(85%)接受了男性伴侣测试,但只有19名男性(10%)参加了测试。在研究过程中,一名妇女进行了血清转化,艾滋病毒累积发生率为0.5%(1/214)。在多变量Logistic回归分析中,家庭与诊所之间的距离较长(aOR 0.87 [95%CI 0.79-0.97])并且不知道家庭收入(aOR 0.30 [95%CI 0.11-0.84])可以预测无法完成连续检测。较高的教育水平与完成连续测试有关(线性趋势p值= 0.05)。总之,部分连续的HIV检测是高度可接受和可行的,但是完成序列检测和男性伴侣检测的吸收率很低。

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