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首页> 外文期刊>AIDS care. >Measuring depression levels in HIV-infected patients as part of routine clinical care using the nine-item Patient Health Questionnaire (PHQ-9).
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Measuring depression levels in HIV-infected patients as part of routine clinical care using the nine-item Patient Health Questionnaire (PHQ-9).

机译：使用九项患者健康调查表（PH​​Q-9），作为常规临床护理的一部分，测量HIV感染患者的抑郁水平。

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摘要

Little is known about the psychometric properties of depression instruments among persons infected with HIV. We analyzed data from a large sample of patients in usual care in two US cities (n=1467) using the nine-item Patient Health Questionnaire (PHQ-9) from the PRIME-MD. The PHQ-9 had curvilinear scaling properties and varying levels of measurement precision along the continuum of depression measured by the instrument. In our cohort, the scale showed a prominent floor effect and a distribution of scores across depression severity levels. Three items had differential item functioning (DIF) with respect to race (African-American vs. white); two had DIF with respect to sex; and one had DIF with respect to age. There was minimal individual-level DIF impact. Twenty percent of the difference in mean depression levels between African-Americans and whites was due to DIF. While standard scores for the PHQ-9 may be appropriate for use with individual HIV-infected patients in cross-sectional settings, these results suggest that investigations of depression across groups and within patients across time may require a more sophisticated analytic framework.
机译：关于艾滋病毒感染者中抑郁仪器的心理测量特性知之甚少。我们使用来自PRIME-MD的九项患者健康调查表（PH​​Q-9）分析了来自美国两个城市（n = 1467）日常护理中大量患者的数据。 PHQ-9具有曲线的缩放特性，并且沿着仪器测量到的连续凹陷具有不同的测量精度水平。在我们的队列中，该量表显示出显着的地板效应，并且在抑郁症严重程度水平之间得分分布。三个项目在种族方面具有不同的项目功能（DIF）（非裔美国人与白人）;两个人在性方面有DIF;一个人的年龄是DIF。个人层面的DIF影响最小。非裔美国人和白人之间平均抑郁水平差异的20％是DIF所致。虽然PHQ-9的标准评分可能适合在横断面环境中与个别HIV感染患者一起使用，但这些结果表明，跨人群和跨患者的抑郁症调查可能需要更复杂的分析框架。

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