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HIV-related neurocognitive impairment screening: The patient's perspective on its utility and psychological impact

机译:HIV相关的神经认知障碍筛查:患者对其效用和心理影响的看法

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Despite ever improving advances in antiretroviral therapy, neurocognitive impairments such as asymptomatic and mild neurocognitive impairment remain a significant problem for the HIV-positive population. We distributed a post-neurocognitive impairment screening service evaluation questionnaire to assess satisfaction and anxiety. Subjects were HIV positive and aged 18-50. They were screened using the Brief Neurocognitive Score and International HIV Dementia Score as well as undergoing screening for anxiety (Generalised Anxiety Disorder Assessment [GAD-7]), depression (Participant Health Questionnaire Mood Scale [PHQ-9]) and memory (Everyday Memory Questionnaire [EMQ-R]). On completion, they were either reassured that the tests were normal or were referred for further investigation. Following assessment, subjects were asked to complete an anonymous satisfaction survey; 101 surveys were analysed. Forty-nine per cent of participants stated that they "felt better" following screening, 43% said it "made no difference", 6% stated it "worried me" and 1% "did not understand". On a scale of 0-10 of helpfulness, the mean score was 7.53. Forty-seven subjects indicated that they were referred for further investigation and 46 subjects that nothing else was needed; 8 reported they did not know. Those referred on rated satisfaction at a mean of 7.54/10 and those with normal screen as 7.09/10 (p = 0.46). Of the groups that were referred for further investigation, 6% said the test "worried them" compared to 4% in the non-referred group. Forty-nine per cent said they "felt better" despite an abnormal result compared to 50% in a normal screening result (p = 0.76). The results of this survey show that screening for neurocognitive impairment by this method is acceptable and helpful to participants. It did not lead to an increase in anxiety and there was no correlation between referred for further investigations and anxiety suggesting concerns about creating undue anxiety by screening and referral are unfounded.
机译:尽管抗逆转录病毒疗法的进步不断提高,但无症状和轻度神经认知功能障碍等神经认知功能障碍仍然是HIV阳性人群的重要问题。我们分发了神经后认知障碍筛选服务评估问卷,以评估满意度和焦虑感。受试者为HIV阳性,年龄为18-50岁。使用简短的神经认知评分和国际HIV痴呆评分对他们进行筛查,并进行焦虑症(广义焦虑症评估[GAD-7]),抑郁症(参与者健康问卷情绪量表[PHQ-9])和记忆力(日常记忆)的筛查问卷[EMQ-R])。完成后,他们可以向他们保证测试是正常的,或者被转交给进一步调查。评估后,要求受试者完成匿名满意度调查;分析了101个调查。 49%的参与者表示他们在筛查后“感觉更好”,43%的参与者表示“没有影响”,6%的参与者表示“担心我”,1%的参与者“不理解”。在0-10的帮助下,平均得分为7.53。 47名受试者表示已将他们转介作进一步调查,46名受试者表示不需要其他物品。 8人报告他们不知道。那些评价的平均满意度为7.54 / 10,而那些正常筛查的人群的满意度为7.09 / 10(p = 0.46)。在被转诊作进一步调查的组中,有6%的人表示测试“令他们感到担忧”,而未转诊的组中这一比例为4%。 49%的人说,尽管结果异常,但他们“感觉更好”,而正常筛查结果为50%(p = 0.76)。这项调查的结果表明,用这种方法筛查神经认知障碍是可以接受的,并且对参与者有帮助。它并没有导致焦虑的增加,转介到进一步的研究与焦虑之间也没有相关性,这表明对通过筛查和转诊而造成过度焦虑的担忧是没有根据的。

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