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首页> 外文期刊>AIDS care. >'I never thought that it would happen...' Experiences of HIV seroconverters among HIV-discordant partnerships in a prospective HIV prevention study in Kenya
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'I never thought that it would happen...' Experiences of HIV seroconverters among HIV-discordant partnerships in a prospective HIV prevention study in Kenya

机译：“我从没想过会发生……”在肯尼亚进行的一项前瞻性艾滋病毒预防研究中，艾滋病毒不同转化伙伴之间的艾滋病毒血清转化者的经验

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摘要

In spite of access to behavioral and biomedical HIV prevention strategies, HIV transmission occurs. For HIV-serodiscordant couples, prevention programs can be tailored to address individual and couples' needs to preserve their relationship while minimizing HIV risk. Programs for serodiscordant couples may benefit from learning from experiences of couples who transmit HIV. We conducted 20 individual in-depth interviews with 10 initially HIV-serodiscordant couples who transmitted HIV during prospective follow-up at a peri-urban research site in Thika, Kenya. Data were analyzed inductively to identify situations that led to prevention failure and coping mechanisms. Inconsistent condom use driven by low HIV risk perception and alcohol use often preceded seroconversion while persistent blame frequently hindered couples' communication soon after seroconversion. In this emerging era of antiretroviral-based HIV prevention, couples' counseling can capitalize on opportunities to foster a supportive environment to discuss initiation and adherence to time-limited pre-exposure prophylaxis and lifelong antiretroviral therapy, in addition to strategies to reduce alcohol use, diffuse blame, and use condoms.
机译：尽管获得了行为和生物医学方面的艾滋病毒预防策略，但仍在传播艾滋病毒。对于艾滋病毒感染力强的夫妇，可以制定预防计划，以解决个人和夫妇在保持艾滋病毒风险的同时保持其关系的需求。从传播艾滋病毒的夫妇的经验中学到的知识可能会有益于针对血清脂溶性伴侣的计划。我们在肯尼亚Thika的一个郊区研究中心对10位最初接受HIV血清不一致的夫妇进行了20次个人深入访谈，这些夫妇在前瞻性随访期间传播了HIV。对数据进行归纳分析，以识别导致预防失败和应对机制的情况。艾滋病毒感染风险低的观念导致避孕套使用不一致，并且在进行血清转换之前经常饮酒，而持续的指责则经常阻碍夫妻在进行血清转换之后的交流。在这个新兴的以抗逆转录病毒为基础的HIV预防时代，夫妇的咨询可以利用机会，营造有利的支持环境，以讨论开始和坚持有时间限制的暴露前预防和终生抗逆转录病毒疗法，以及减少饮酒的策略，散布责备，并使用避孕套。

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