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首页> 外文期刊>AIDS care. >Longitudinal predictors of depressive symptoms among low income injection drug users.
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Longitudinal predictors of depressive symptoms among low income injection drug users.

机译：低收入注射吸毒者中抑郁症状的纵向预测因素。

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摘要

Effects of changes in physical health status and drug use, and prior social support on depressive symptoms were assessed in low income injection drug users. Data are from participants (n = 503) enrolled at baseline (1994-1995) who remained at one-year follow-up (79%), of whom 37% were HIV-positive and 36% female. Physical health was measured by HIV symptoms, AIDS, CD4 count and functional limitation (IADLs). One-third scored high on depressive symptoms (CES-D > or = 16) at one-year follow-up, representing no statistically significant change from baseline (38%). In multiple logistic regression, after controlling for baseline depression scores (OR = 6.11, p < 0.001) and drug use (OR = 1.20, p = 0.192), baseline functional limitation (OR = 3.28, p < 0.001) and declining functioning (OR = 3.60, p < 0.001) were positively, and quitting drug use was negatively, associated with depressive symptoms at follow-up. Low social support at baseline (OR = 0.58, p < 0.10) was marginally predictive of depressive symptoms. Depressive symptoms did not differ by gender. For HIV-positive respondents, functional limitation was predictive of depressive symptoms, but HIV illness and drug use were not. Facilitating drug treatment and preventive medical care may aid in reducing depression in this population. For HIV-positive drug users, drug treatment prior to AIDS may help reduce depressive symptoms, with potential implications for HIV service utilization and medical adherence.
机译：在低收入注射吸毒者中评估了身体健康状况和药物使用的变化以及先前的社会支持对抑郁症状的影响。数据来自于基线（1994-1995年）入组的参与者（n = 503），他们接受了一年的随访（79％），其中37％是HIV阳性，36％是女性。通过HIV症状，AIDS，CD4计数和功能限制（IADL）来衡量身体健康。三分之一的患者在一年的随访中抑郁症状得分较高（CES-D>或= 16），与基线相比无统计学差异（38％）。在多元逻辑回归中，在控制了基线抑郁评分（OR = 6.11，p <0.001）和药物使用（OR = 1.20，p = 0.192），基线功能受限（OR = 3.28，p <0.001）和功能下降（OR）之后= 3.60，p <0.001）为阳性，戒烟为阴性，与随访时的抑郁症状相关。基线时较低的社会支持（OR = 0.58，p <0.10）只能轻微预测抑郁症状。抑郁症状没有性别差异。对于艾滋病毒呈阳性的受访者，功能限制是抑郁症状的预言，而艾滋病毒的疾病和吸毒却并非如此。促进药物治疗和预防性医疗保健可能有助于减少该人群的抑郁症。对于HIV阳性吸毒者，在AIDS之前进行药物治疗可能有助于减轻抑郁症状，对HIV服务利用和医疗依从性有潜在影响。

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